Spanish Multicenter Normative Studies (Neuronorma Project): Norms for the Abbreviated Barcelona Test

Quintana, M.; Peña-Casanova, Jordi; Sánchez‐Benavides, Gonzalo; Langohr, Klaus; Manero, R.M.; Aguilar, Miguel; Badenes, Dolors; Molinuevo, José Luís; Robles, Alfredo; Barquero, María Sagrario; Antúnez, Carmen; Martínez-Parra, Carlos; Frank-García, Ana; Fernández, Manuel Montanero; Blesa, Rafael; Oliva, R.M.; Gómez‐Anson, Beatriz; Monté, Gemma C.; Alayrach, Elena; Sainz, Aitor; Caprile, Claudia; Sánchez, Gonzalo García de Casasola; Gramunt, Nina; Böhm, Peter; González, Sonia; Buriel, Yolanda; Quiñones, Sonia; Cucurella, Gràcia; Ruiz, Estibaliz; Serradell, Mónica; Torner, Laura; Casas, Laura; Cerulla, Noemí; Ramos, Silvia Camino; Cabello, Loli; Rodríguez, Dolores; Payno, María; Villanueva, Clara; Carles, Rafael; Jiménez, Judit; Antequera, Martirio; Gata, Jose Manuel; Duque, Pablo; Jiménez, Laura; Sanz, Azucena; Aguilar, M.A.; Molano, Ana; Lasa, Maitena; Sol, Josep M.; Hernández, Francisco Heras; Quevedo, Irune; Salvà, Anna; Alfonso, Verónica; Pla, Carme; Ribas, Romina; Lonsdale, Stephanie

doi:10.1093/arclin/acq098

Cited by 37 publications

(21 citation statements)

References 46 publications

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“…To aid this process, projects like the Spanish Multicenter Normative Studies (NEURONORMA) have been adapting English language tests for the Spanish-speaking population [10], [11], [12], [13], [14]. A few neuropsychological screening batteries, adapted for Spanish-speaking individuals, have also been adapted to include age and education adjusted normative values [15], [16], [17], [18], [19]. All of these tests were standardized by administering them to a representative sample of cognitively healthy individuals to establish normative scores.…”

Section: Introductionmentioning

confidence: 99%

Cut-off Scores of a Brief Neuropsychological Battery (NBACE) for Spanish Individual Adults Older than 44 Years Old

et al. 2013

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The neuropsychological battery used in Fundació ACE (NBACE) is a relatively brief, and easy to administer, test battery that was designed to detect cognitive impairment in the adulthood. The NBACE includes measures of cognitive information processing speed, orientation, attention, verbal learning and memory, language, visuoperception, praxis and executive functions. The aim of the present study was to establish the cut-off scores for impairment for different levels of age and education that could be useful in the cognitive assessment of Spanish subjects who are at risk for cognitive impairment, especially dementia. Data from 1018 patients with a mild dementia syndrome, and 512 cognitively healthy subjects, older than 44 years, from the Memory Clinic of Fundació ACE (Barcelona, Spain) were analyzed. In the whole sample, cut-off scores and sensitivity/specificity values were calculated for six conditions after combining 3 age ranges (44 to 64; 65 to 74; and older than 74 years old) by 2 educational levels (until Elementary school; and more than Elementary school). Moreover, general cut-offs are reported for Catalan and Spanish speakers. The results showed that most of NBACE tests reached good sensitivity and specificity values, except for Ideomotor praxis, Repetition and Verbal Comprehension tests, which had a ceiling effect. Word List Learning from the Wechsler Memory Scale-III and Semantic Verbal Fluency were the most useful tests to discriminate between cognitively healthy and demented subjects. The NBACE has been shown to be a useful tool able to detect cognitive impairment, especially dementia, in older than 44 years Spanish persons.

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Section: Introductionmentioning

confidence: 99%

Cut-off Scores of a Brief Neuropsychological Battery (NBACE) for Spanish Individual Adults Older than 44 Years Old

et al. 2013

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“…Although it is generally accepted that attention and executive measures are impaired faster than memory, language and perceptive domains throughout normal aging, the examination of attention on ACE-III includes orientation, repetition of 3 words, and a serial subtraction task. These items are less influenced by age than other more demanding attentional and executive tasks, such as verbal fluency [13]. …”

Section: Discussionmentioning

confidence: 99%

Normative Data for the Spanish Version of the Addenbrooke's Cognitive Examination III

Matías‐Guiu

Fernández-Bobadilla

Fernández-Oliveira³

et al. 2016

Dement Geriatr Cogn Disord

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Background: Addenbrooke's Cognitive Examination III (ACE-III) is a cognitive test that has been validated for the diagnosis of cognitive disorders. The aim of this study was to provide normative data for the ACE-III for age, education and gender. Methods: The Spanish version of the ACE-III was administered to a group of 273 healthy subjects in a multicenter study in Spain. Correlation and determination coefficients for age, education and gender were estimated. The overlapping interval strategy and linear regression analyses were used to provide adjusted norms for demographic factors and to explore the potential influence of these factors in the performance of the test. Results: Age and education correlated significantly with the total score and with all the domains. Gender correlated only with the domains of attention and visuospatial skills. Norms for the total score and for cognitive domains (attention, memory, fluency, language, and visuospatial skills) are provided. Conclusion: This study confirms the influence of demographic factors (especially age and education) on the performance in the ACE-III and provides normative data for the Spanish version of the ACE-III.

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“…Language examination included the evaluation of verbal expression and comprehension, repetition, and naming. Tests used for this purpose included the Boston Naming Test, letter/word verbal fluency, ''Cookie Theft'' picture from Boston Diagnostic Aphasia Examination, and language subtests of the Barcelona Test [17]. The Progressive Aphasia Severity Score (PASS) was used to grade the severity of language impairment [18].…”

Section: Patient Selection and Assessmentmentioning

confidence: 99%

Clinical course of primary progressive aphasia: clinical and FDG-PET patterns

et al. 2014

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Primary progressive aphasia (PPA) may be the onset of several neurodegenerative diseases. This study evaluates a cohort of patients with PPA to assess their progression to different clinical syndromes, associated factors that modulate this progression, and patterns of cerebral metabolism linked to different clinical evolutionary forms. Thirty-five patients meeting PPA criteria underwent a clinical and neuroimaging (18)F-Fluorodeoxyglucose PET evaluation. Survival analysis was performed using time from clinical onset to the development of a non-language symptom or deficit (PPA-plus). Cerebral metabolism was analyzed using Statistical Parametric Mapping. Patients classified into three PPA variants evolved to atypical parkinsonism, behavioral disorder and motor neuron disease in the agrammatic variant; to behavioral disorder in the semantic; and to memory impairment in the logopenic. Median time from the onset of symptoms to PPA-plus was 36 months (31-40, 95 % confidence interval). Right laterality, and years of education were associated to a lower risk of progression, while logopenic variant to a higher risk. Different regions of hypometabolism were identified in agrammatic PPA with parkinsonism, motor neuron disease and logopenic PPA-plus. Clinical course of PPA differs according to each variant. Left anterior temporal and frontal medial hypometabolism in agrammatic variant is linked to motor neuron disease and atypical parkinsonism, respectively. PPA variant, laterality and education may be associated to the risk of progression. These results suggest the possibility that clinical and imaging data could help to predict the clinical course of PPA.

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Spanish Multicenter Normative Studies (Neuronorma Project): Norms for the Abbreviated Barcelona Test

Cited by 37 publications

References 46 publications

Cut-off Scores of a Brief Neuropsychological Battery (NBACE) for Spanish Individual Adults Older than 44 Years Old

Cut-off Scores of a Brief Neuropsychological Battery (NBACE) for Spanish Individual Adults Older than 44 Years Old

Normative Data for the Spanish Version of the Addenbrooke's Cognitive Examination III

Clinical course of primary progressive aphasia: clinical and FDG-PET patterns

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