Spanish population data on the four STR loci D8S1179, D16S539, D18S51 and D21S11

Martı́n, Pablo; Garcı́a, Oscar; Albarrán, Cristina; García, Pilar Peral; Sancho, Manuel; Alonso, Antonio

doi:10.1007/s004140050266

Cited by 4 publications

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Parentage testing with 14 STR loci and population data for 5 STRs in the Slovenian population

Pajnic

et al. 2001

International Journal of Legal Medicine

View full text Add to dashboard Cite

In order to apply a set of 14 short tandem repeat (STR) loci in parentage testing, we performed a population genetic study on a sample of 260 unrelated people from the Slovenian population. Genotypes for the 14 STRs were determined using three multiplex polymerase chain reactions (PCR) and automated fluorescent detection. The allele frequencies of the STR loci D5S818, D13S317, D7S820, D8S1179 and D18S51 showed no deviation from the Hardy-Weinberg equilibrium and agreed well with other Caucasian populations. We resolved a series of 181 parentage disputes of which 29 were exclusions. In all cases, evidence for exclusion was obtained by at least 4 informative STRs out of the 14 loci analysed. The 14 loci combined comprise a highly discriminating test suitable for paternity and identity testing in the Slovenian population, with an average estimated mutation rate of 1.2x10(-3), a combined calculated power of exclusion of 99.99974% and paternity index (PI) value of >10(6) in 72% of the inclusion cases and >10(5) in 91% of the inclusion cases.

show abstract