Spatial Analysis of Metal–PLGA Hybrid Microstructures Using 3D SERS Imaging

Strozyk, Malte S.; Aberasturi, Dorleta Jiménez de; Gregory, Jeffrey A.; Lahann, Joerg; Liz‐Marzán, Luis M.

doi:10.1002/adfm.201701626

Cited by 42 publications

(42 citation statements)

References 42 publications

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“…Special attention can be given to intelligent polymers in which special resources are added to the colloidal compounds, making them sensitive to the stimuli employed, changing their properties, such as temperature, ionic strength, solvent polarity, electric/magnetic field, light or biomolecules. 133,134 Using smart polymers responding to stimuli are delivery vehicles that are being considered as promising for controlled encapsulation and release of drugs. 135,136 In the study, gadolinium oxide and europium-encapsulated temperature/pH-responsive polymeric particles (PLTPPs) were synthesized by emulsifier-free emulsion polymerization presented excellent biocompatibility with C6 cellulases and anticancer drug loading capacity (doxorubicin, DOX).…”

Section: Smart Supportmentioning

confidence: 99%

Design of Immobilized Enzyme Biocatalysts: Drawbacks and Opportunities

Reis

Sousa

Serpa

et al. 2019

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The enzymatic processes are increasingly highlights, especially in the synthesis of chemical products with high added value. The enzyme immobilization can improve industrial biocatalytic processes. The immobilization of enzymes provides the production of efficient, stable biocatalysts, possibility of reuse and easy purification of the products, when compared to the free enzymes. There is a growing research for more efficient methods of enzyme immobilization. In this context, the choice of support and immobilization strategy can significantly improve the final enzymatic properties. In this review paper, we aimed to discuss the versatility of biocatalysts immobilized enzymes design, focusing on the opportunities and disadvantages for each method presented. They discussed the recent development of enzyme immobilization methods and applications relating the final properties of the produced biocatalysts with the desired goals.

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Section: Smart Supportmentioning

confidence: 99%

Design of Immobilized Enzyme Biocatalysts: Drawbacks and Opportunities

Reis

Sousa

Serpa

et al. 2019

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“…Such accurate label‐free and fingerprint detection technique has been considered as a promising and noninvasive POC diagnostic tool in various applications, such as environmental monitoring, drug detection, explosives analyses, as well as healthcare inspection . Due to small scattering cross sections of the detected molecules, a plenty of plasmonic nanostructures primarily based on the electromagnetic field enhancement are widely investigated, which usually rely on chemical syntheses or complex lithographic approaches to achieve high‐density of hotspots . Among them, laser processing is an intriguing approach to fabricate micro/nanostructures over a large area at a high speed .…”

Section: Introductionmentioning

confidence: 99%

Hedgehog Inspired CuO Nanowires/Cu₂O Composites for Broadband Visible‐Light‐Driven Recyclable Surface Enhanced Raman Scattering

Yan

Tan

et al. 2018

Advanced Optical Materials

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Self‐cleanable surface‐enhanced Raman scattering (SERS) spectroscopy affords a promising route toward environment‐friendly biosensors for point‐of‐care diagnostics. It is of great importance to develop recyclable SERS substrates driven by a photocatalytic decomposition process, especially in the visible range. In this work, inspired by the hedgehog‐like structures, a broadband visible‐light‐driven photocatalytic SERS platform with the CuO nanowires (NWs)/Cu2O hetero‐nanostructures as the backbone is demonstrated. Via employing the approach of nanosecond laser ablation on Cu sheet coupled with subsequent thermal oxidation, the formed hedgehog‐like, high‐density, and dual‐scale micro/nanostructures not only demonstrate enhanced broadband visible‐light‐absorption capability even extended to the near infrared range but also exhibit boosted interfacial adhesion with favorable stability. Such phenomena imply that the binary oxidized Cu composites decorated with metallic nanoparticles can serve as high‐performance SERS substrates with superior recyclability. Under the visible light illumination, the as‐fabricated ternary Ag/CuO NWs/Cu2O composites can be self‐cleaned by photocatalytic degradation of adsorbates, thus leading to recyclable SERS substrates, which can preserve more than 85% SERS activity after seven cycles' measurement. These results pave a new path to realize reusable SERS substrates in the applications of remote and resource‐limited environments toward next‐generation green biosensors.

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“…[36][37][38][39] It can be attributed to the separation of dye molecules inside the polymer suppressing their intramolecular torsional motion. 40,41 Likewise, to evaluate the stability of PSCR brous membranes, when the excitation wavelength is changed from 325 nm to 385 nm, the PSCR membrane always emits white light. When the excitation wavelength is greatly changed, there is only a small change in white light emission ( Fig.…”

Section: Pscr Brous Membranesmentioning

confidence: 99%