Spatial and Temperature Resolutions of Magnetic Nanoparticle Temperature Imaging with a Scanning Magnetic Particle Spectrometer

Abstract

This paper quantitatively investigates the spatial and temperature resolutions of magnetic nanoparticle (MNP) temperature imaging with a multiline phantom filled with MNPs. The multiline phantom in total consists of seven lines with different distances between two adjacent lines. A scanning magnetic particle spectrometer is used to measure the spatial distributions of the MNP harmonics for MNP concentration and temperature imaging, whereas an iterative deconvolution method is used to improve the spatial resolution. A modulation transfer function calculated from the MNP concentration image is used to quantitatively present the spatial resolution, whereas the standard deviation of the measured temperatures is used to quantitatively present the temperature resolution. The spatial resolution is about 4 mm while the temperature resolution is about 1.0 K without deconvolution. With increasing the number of the iterative loops in the deconvolution, the spatial resolution is improved to 2 mm while the temperature resolution is worsened to about 9.6 K due to deconvolution-based oscillation.

Theoretical Analysis for Wireless Magnetothermal Deep Brain Stimulation Using Commercial Nanoparticles

“…In addition, as technologies for measuring particle temperatures in the brain are advancing, monitoring schemes for MNP temperatures such as magnetic particle imaging (MPI) [24] should be incorporated in the WMS process. Moreover, since this simulation assumes that the MNPs are injected directly into the stimulation area, we need to consider how MNPs can reach into the stimulation area.…”

Adaptive Model for Magnetic Particle Mapping Using Magnetoelectric Sensors

“…MNPs can be imaged in a variety of ways. MNP imaging techniques that use MNP as tracer material include Magnetic Particle Imaging (MPI) [ 8 , 9 , 10 ], Scanning Magnetic Particle Spectrometry (SMPS) [ 11 , 12 , 13 , 14 ], Magnetorelaxometry Imaging (MRXI) [ 15 , 16 , 17 , 18 ] and Magneto Acoustic Tomography (MAT) [ 19 , 20 , 21 ]. Another type of MNP imaging technique can be categorized into Magnetic Susceptibility Imaging (MSI) [ 22 ], one of which is called Susceptibility Magnitude Imaging (SMI) [ 23 ].…”

Reversible magnetism switching of iron oxide nanoparticle dispersions by controlled agglomeration

“…[13][14][15] To acquire 2D images by nanoparticle temperature imaging or magnetic particle imaging, thermometry was successfully combined with a spatially scanning setup. [16][17][18] Different magnetic properties at different temperatures yielded a high contrast, indicating the need to design nanoparticles that change their magnetization even more rapidly and strongly near room temperature. 19,20 In this work, we studied the change of magnetic properties in superparamagnetic iron oxide nanoparticles (SPIONs) upon thermally induced agglomeration.…”