2003
DOI: 10.1093/aje/kwg090
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Spatial Clustering of Amyotrophic Lateral Sclerosis in Finland at Place of Birth and Place of Death

Abstract: Previous evidence for spatial clustering of amyotrophic lateral sclerosis is inconclusive. Studies that have identified apparent clusters have often been based on a small number of cases, which means the results may have occurred by chance processes. Also, most studies have used the geographic location at the time of death as the basis for cluster detection, rather than exploring clusters at other points in the life cycle. In this study, the authors examine 1,000 cases of amyotrophic lateral sclerosis distribu… Show more

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Cited by 104 publications
(79 citation statements)
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“…rophy leading to death 1,2 . The pathophysiology of ALS is still poorly known, and the clinical characteristics currently described remain very similar to the original description of Charcot, at the 19 th century 3 .…”
mentioning
confidence: 99%
“…rophy leading to death 1,2 . The pathophysiology of ALS is still poorly known, and the clinical characteristics currently described remain very similar to the original description of Charcot, at the 19 th century 3 .…”
mentioning
confidence: 99%
“…For å unngå problemet med multiple hypotesetester bestemmes antall klynger a priori. Programmet er blant annet brukt for å studere klynger av leukemi blant barn i Sverige (Hjalmers et al 1996) og amytrofisk lateralsklerose i Finland (Sabel et al 2003).…”
Section: Risiko Knyttet Til Ikke-spesifikke Punktkilderunclassified
“…É caracterizada principalmente por fraqueza e atrofia muscular e possui um prognóstico desfavorável [1][2][3] .…”
Section: Introductionunclassified