Spatio-temporal tuning of coherent motion evoked responses in 4–6 month old infants and adults

Hou, Chenping; Gilmore, Rick O.; Pettet, Mark W.; Norcia, Anthony M.

doi:10.1016/j.visres.2009.08.007

Cited by 40 publications

(36 citation statements)

References 58 publications

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“…This is an important point because most studies of human infants and children test one spatial scale or dot speed. The developmental profile obtained will depend on what displacement or speed values are chosen (see also, Ellemberg et al, 2004; Hou et al, 2009; Hayward et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Development of sensitivity to global form and motion in macaque monkeys (Macaca nemestrina)

et al. 2012

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To explore the relative development of the dorsal and ventral extrastriate processing streams, we studied the development of sensitivity to form and motion in macaque monkeys (Macaca nemestrina). We used Glass patterns and random dot kinematograms (RDK) to assay ventral and dorsal stream function, respectively. We tested 24 animals, longitudinally or cross-sectionally, between the ages of 5 weeks and 3 years. Each animal was tested with Glass patterns and RDK stimuli with each of two pattern types – circular and linear – at each age using a two alternative forced-choice task. We measured coherence threshold for discrimination of the global form or motion pattern from an incoherent control stimulus. Sensitivity to global motion appeared earlier than to global form and was higher at all ages, but performance approached adult levels at similar ages. Infants were most sensitive to large spatial scale (Δx) and fast speeds; sensitivity to fine scale and slow speeds developed more slowly independently of pattern type. Within the motion domain, pattern type had little effect on overall performance. However, within the form domain, sensitivity for linear Glass patterns was substantially poorer than that for concentric patterns. Our data show comparatively early onset for global motion integration ability, perhaps reflecting early development of the dorsal stream. However, both pathways mature over long time courses reaching adult levels between two and three years after birth.

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Section: Discussionmentioning

confidence: 99%

Development of sensitivity to global form and motion in macaque monkeys (Macaca nemestrina)

et al. 2012

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“…All recordings were binocular in order to minimize the testing time and to avoid artefacts due to inattention. The display and data acquisition have been described in detail elsewhere 18 and were controlled by PowerDiva v.2.90 software (A M Norcia, Smith Kettlewell Eye Institute, San Francisco, USA). Display resolution was set at 1600×1200 pixels (eight bits) with a refresh rate of 60Hz.…”

Section: Methodsmentioning

confidence: 99%

Defective motion processing in children with cerebral visual impairment due to periventricular white matter damage

Weinstein

Gilmore

Shaikh

et al. 2011

Develop Med Child Neuro

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Aim We sought to characterize visual motion processing in children with cerebral visual impairment (CVI) due to periventricular white matter damage caused by either hydrocephalus (eight individuals) or periventricular leukomalacia (PVL) associated with prematurity (11 individuals). Method Using steady‐state visually evoked potentials (ssVEP), we measured cortical activity related to motion processing for two distinct types of visual stimuli: ‘local’ motion patterns thought to activate mainly primary visual cortex (V1), and ‘global’ or coherent patterns thought to activate higher cortical visual association areas (V3, V5, etc.). We studied three groups of children: (1) 19 children with CVI (mean age 9y 6mo [SD 3y 8mo]; 9 male; 10 female); (2) 40 neurologically and visually normal comparison children (mean age 9y 6mo [SD 3y 1mo]; 18 male; 22 female); and (3) because strabismus and amblyopia are common in children with CVI, a group of 41 children without neurological problems who had visual deficits due to amblyopia and/or strabismus (mean age 7y 8mo [SD 2y 8mo]; 28 male; 13 female). Results We found that the processing of global as opposed to local motion was preferentially impaired in individuals with CVI, especially for slower target velocities (p=0.028). Interpretation Motion processing is impaired in children with CVI. ssVEP may provide useful and objective information about the development of higher visual function in children at risk for CVI.

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“…Neural responses to motion coherence (Hou, Gilmore, Pettet, & Norcia, 2009) are seen earlier in development than global form responses (Palomares et al, 2010), and are more robust to prolonged visual deprivation (Fine et al, 2003). Moreover, motion captures attention automatically (Franconeri & Simons, 2003), suggesting that the coherent motion system is, perhaps, computationally simpler or more 'hard-wired' than the form system.…”

Section: Intrinsic Salience Of Global Form and Motionmentioning

confidence: 99%

Distinct effects of attention on the neural responses to form and motion processing: A SSVEP source-imaging study

et al. 2012

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We measured neural responses to local and global aspects of form and motion stimuli using frequency-tagged, steady-state visual evoked potentials (SSVEPs) combined with magnetic resonance imaging (MRI) data. Random dot stimuli were used to portray either dynamic Glass patterns (Glass, 1969) or coherent motion displays. SSVEPs were used to estimate neural activity in a set of fMRI-defined visual areas in each subject. To compare activity associated with local versus global processing, we analyzed two frequency components of the SSVEP in each visual area: the high temporal frequency at which the local dots were updated (30 Hz) and the much lower frequency corresponding to updates in the global structure (0.83 Hz). Local and global responses were evaluated in the context of two different behavioral tasks--subjects had to either direct their attention toward or away from the global coherence of the stimuli. The data show that the effect of attention on global and local responses is both stimulus and visual area dependent. When attention was directed away from stimulus coherence, both local and global responses were higher in the coherent motion than Glass pattern condition. Directing attention to coherence in Glass patterns enhanced global activity in areas LOC, hMT+, V4, V3a, and V1, while attention to global motion modulated responses by a smaller amount in a smaller set of areas: V4, hMT+, and LOC. In contrast, directing attention towards stimulus coherence weakly increased local responses to both coherent motion and Glass patterns. These results suggest that visual attention differentially modulates the activity of early visual areas at both local and global levels of structural encoding.

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Spatio-temporal tuning of coherent motion evoked responses in 4–6 month old infants and adults

Cited by 40 publications

References 58 publications

Development of sensitivity to global form and motion in macaque monkeys (Macaca nemestrina)

Development of sensitivity to global form and motion in macaque monkeys (Macaca nemestrina)

Defective motion processing in children with cerebral visual impairment due to periventricular white matter damage

Distinct effects of attention on the neural responses to form and motion processing: A SSVEP source-imaging study

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