Spatiotemporal changes in neural response patterns to faces varying in visual familiarity

Natu, Vaidehi; O'Toole, Alice J.

doi:10.1016/j.neuroimage.2014.12.027

Cited by 25 publications

(20 citation statements)

References 48 publications

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“…Furthermore, these latter regions did not exhibit significant familiarity-dependent differences in their overall response. Therefore, taken together, these findings do not support the view that explicit familiarity decisions involve initial assessment of the known-versus-unknown status of faces within core posterior facepreferential areas, which would then be propagated to anterior regions of the extended face-processing system involved in storage of semantic information and affective processing (16,20,35). Rather, following a detailed analysis of individual faces in posterior regions of the core network, the categorical distinction between personally familiar and unfamiliar faces appears to emerge in anterior ventral and medial temporal regions.…”

Section: Discussionmentioning

confidence: 80%

“…(For a recent discussion of this issue, see ref. 20.) Previous findings suggest that the high saliency and association with numerous past experiences, which are characteristic of personally meaningful stimuli, lead to the involvement of larger proportions of the brain (51), in particular, within medial and anterior temporal regions (30,52,53).…”

Section: Significancementioning

confidence: 99%

“…For example, within the right FFA, face familiarity has been associated with either increased or decreased neural activation (18,19). Moreover, only subtle differences in the patterns of voxels activated for (visually) familiar versus unfamiliar faces have been described in the OFA and FFA, in some but not all studies (20). These relatively weak and inconsistent differences between the neural representations of familiar and unfamiliar faces are at odds with the large differences observed behaviorally (21,22).…”

mentioning

confidence: 99%

“…According to one view, core face-preferential areas could rapidly assess the "knownversus-unknown" status of faces, sending information forward to anterior regions of the extended face-processing system for storage and affective processing (16,20,35). Alternatively, following a detailed analysis of individual faces in posterior regions of the core network, the categorization of faces according to their familiarity might be determined (i.e., emerge) first and foremost in anterior ventral and medial temporal regions.…”

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confidence: 99%

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Neural microgenesis of personally familiar face recognition

Ramon

Vizioli

Liu‐Shuang³

et al. 2015

Proc. Natl. Acad. Sci. U.S.A.

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Despite a wealth of information provided by neuroimaging research, the neural basis of familiar face recognition in humans remains largely unknown. Here, we isolated the discriminative neural responses to unfamiliar and familiar faces by slowly increasing visual information (i.e., high-spatial frequencies) to progressively reveal faces of unfamiliar or personally familiar individuals. Activation in ventral occipitotemporal face-preferential regions increased with visual information, independently of long-term face familiarity. In contrast, medial temporal lobe structures (perirhinal cortex, amygdala, hippocampus) and anterior inferior temporal cortex responded abruptly when sufficient information for familiar face recognition was accumulated. These observations suggest that following detailed analysis of individual faces in core posterior areas of the face-processing network, familiar face recognition emerges categorically in medial temporal and anterior regions of the extended cortical face network.personally familiar face recognition | coarse-to-fine | fusiform face area | amygdala | medial temporal lobe

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Section: Discussionmentioning

confidence: 80%

Section: Significancementioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Neural microgenesis of personally familiar face recognition

Ramon

Vizioli

Liu‐Shuang³

et al. 2015

Proc. Natl. Acad. Sci. U.S.A.

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“…Pictures of personally familiar objects (PFO) were taken from toys with which the subjects interact daily (see SM). This minimized two typical problems of stimulus design in the study of familiarity: (i) intersubject variability in the degree of familiarity and (ii) the picture-specific nature of visually familiarized stimuli (24, 25). All temporal and prefrontal face areas (mapped with an independent Face Localizer Experiment; see SM) were activated more by PFF than by PFO (Fig.…”

mentioning

confidence: 99%

Two areas for familiar face recognition in the primate brain

Landi¹,

Freiwald²

2017

Science

117

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Familiarity alters face recognition: Familiar faces are recognized more accurately than unfamiliar ones, and under difficult viewing conditions when unfamiliar face recognition fails. The neural basis for this fundamental difference remains unknown. Using whole-brain functional magnetic resonance imaging, we found that personally familiar faces engage the macaque face-processing network more than unfamiliar faces. Familiar faces also recruited two hitherto unknown face areas at anatomically conserved locations within the perirhinal cortex and the temporal pole. These two areas, but not the core face-processing network, responded to familiar faces emerging from a blur with a characteristic nonlinear surge, akin to the abruptness of familiar face-recognition. In contrast, responses to unfamiliar faces and objects remained linear. Thus two temporal lobe areas extend the core face-processing network into a familiar face recognition system.

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