Spatiotemporal patterns of ontogenetic expression of parvalbumin in the superior colliculi of rats and rabbits

Barker, David; Dreher, Bogdan

doi:10.1002/(sici)1096-9861(19980406)393:2<210::aid-cne6>3.0.co;2-5

Cited by 14 publications

(8 citation statements)

References 83 publications

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“…A similar pattern of one single tier of PV immunoreactivity has been reported in the SC of cats (Mize et al, 1992) and humans (Leuba and Saini, 1996). In the cat, however, unlike in rats (Illing et al, 1990; Schmidt‐Kastner et al, 1992; Lane et al, 1996, 1997; Barker and Dreher, 1998) and humans (Leuba and Saini, 1996), the dense band of PV immunoreactivity does not include the upper SGS and SZ but spreads substantially to the dorsal SO. In the rat SC, the PV immunoreactivity shows a characteristic distribution and the SGS is homogeneously stained.…”

Section: Discussionmentioning

confidence: 99%

Calbindin D28k and parvalbumin immunoreactivity in the rabbit superior colliculus: An anatomical study

et al. 2000

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The expression pattern of two calcium binding proteins (CaBP), calbindin D28k (CB) and parvalbumin (PV), in the superior colliculus (SC) of the adult rabbit, as well as the morphology of the immunoreactive cells were examined. The study was performed on 12 rabbits. Coronal sections from postmortem SC were analyzed by light microscopy, and drawings of CaBP‐labeled cells were obtained using a drawing tube. No previous information is available on either the CB/PV expression or the morphology of CB/PV positive cells in the SC of the adult rabbit. Therefore, in this study we show that CB neurons and neuropil form three main tiers: the first located within the stratum zonale (SZ) and the upper part of the stratum griseum superficiale (SGS), the second located within the stratum griseum intermedium (SGI), and the third, located within the medial and central areas of the stratum griseum profundum (SGP). In contrast to this layer labeling, almost no CB‐positivity is found within the other collicular layers. On the other hand, the densest concentration of PV labeled cells and terminals is found within a single dense tier that spanned the ventral part of the startum griseum superficiale (SGS) and the dorsal part of the stratum opticum (SO). Anti‐PV neurons are also scattered through the deeper layers below the dense tier. In contrast, almost no anti‐PV labeled neurons or neuropil are found within the stratum zonale (SZ) and upper SGS. This distribution represents a new pattern of sublamination in the SC of this species. All the previously described cell types in other mammals are observed in the rabbit SC: marginal cells, horizontal cells, pyriform cells, narrow‐field vertical cells, wide‐field vertical cells, and stellate/multipolar cells. Detailed drawings of all these cellular types are represented to show their complete morphology. The results of this study indicate that both CB and PV are present in a variety of neurons, which present a number of homologies between mammals, but have a different location and/or distribution, according to the different species. These findings are thus relevant to better understand the organisation of the SC in mammals. Anat Rec 259:334–346, 2000. © 2000 Wiley‐Liss, Inc.

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Section: Discussionmentioning

confidence: 99%

Calbindin D28k and parvalbumin immunoreactivity in the rabbit superior colliculus: An anatomical study

et al. 2000

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“…The mammalian superior colliculi form laminated eminences on the rostral half of the tectum of the midbrain. Although studies have established the architecture of the mammalian superior colliculus in different species, notably the rat (Altman & Carpenter, 1961; Brodal, 1972; Harting, 1977; Graybiel, 1978), rabbit (Barker & Dreher, 1998; Gonzalez‐Soriano et al. 2000; McHaffie et al.…”

Section: Introductionmentioning

confidence: 99%

The superior colliculus of the camel: a neuronal‐specific nuclear protein (NeuN) and neuropeptide study

Mensah-Brown

Garey

2006

Journal of Anatomy

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In this study we examined the superior colliculus of the midbrain of the one-humped (dromedary) camel, Camelus dromedarius , using Nissl staining and anti-neuronal-specific nuclear protein (NeuN) immunohistochemistry for total neuronal population as well as for the enkephalins, somatostatin (SOM) and substance P (SP). It was found that, unlike in most mammals, the superior colliculus is much larger than the inferior colliculus. The superior colliculus is concerned with visual reflexes and the co-ordination of head, neck and eye movements, which are certainly of importance to this animal with large eyes, head and neck, and apparently good vision. The basic neuronal architecture and lamination of the superior colliculus are similar to that in other mammals. However, we describe for the first time an unusually large content of neurons in the superior colliculus with strong immunoreactivity for met-enkephalin, an endogenous opioid. We classified the majority of these neurons as small (perimeters of 40-50 µ m), and localized diffusely throughout the superficial grey and stratum opticum. In addition, large pyramidal- immunopositive to SOM and SP were located exclusively in the superficial grey layer. We propose that this system may be associated with a pain-inhibiting pathway that has been described from the periaqueductal grey matter, juxtaposing the deep layers of the superior colliculus, to the lower brainstem and spinal cord. Such pain inhibition could be important in relation to the camel's life in the harsh environment of its native deserts, often living in very high temperatures with no shade and a diet consisting largely of thorny branches.

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“…Prominent examples of transneuronal anterograde degeneration after experimental deafferentation comprise apoptosis of cortical sensory neurons after deafferentation injury (Capurso et al, 1997) and degeneration of hippocampal granule cells after loss of input in the pilocarpine model of epilepsy (Marques-Mari et al, 2007). As shown before, PVexpressing neurons of the superior colliculus and the spinal cord are particularly vulnerable to afferent lesions (Barker and Dreher, 1998;Dekkers et al, 2002). In the current study, we provide direct evidence that also the PV-positive neurons of the Rt can be the target of transneuronal anterograde degeneration.…”

Section: Discussionmentioning

confidence: 55%

Thalamocortical Pathfinding Defects Precede Degeneration of the Reticular Thalamic Nucleus in Polysialic Acid-Deficient Mice

Schiff¹,

Röckle²,

Burkhardt³

et al. 2011

J. Neurosci.

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IVϪ/Ϫ ) mice characterized by severe defects of major brain axon tracts, including internal capsule hypoplasia. Here, we demonstrate that misguidance of thalamocortical fibers and deficiencies of corticothalamic connections contribute to internal capsule defects in II Ϫ/Ϫ IV Ϫ/Ϫ mice. Thalamocortical fibers cross the primordium of the reticular thalamic nucleus (Rt) at embryonic day 14.5, before they fail to turn into the ventral telencephalon, thus deviating from their normal trajectory without passing through the internal capsule. At postnatal day 1, a reduction and massive disorganization of fibers traversing the Rt was observed, whereas terminal deoxynucleotidyl transferase dUTP nick end labeling and cleaved caspase-3 staining indicated abundant apoptotic cell death of Rt neurons at postnatal day 5. Furthermore, during postnatal development, the number of Rt neurons was drastically reduced in 4-week-old IIN Ϫ/Ϫ triple knock-out animals displaying no internal capsule defects. Thus, degeneration of the Rt in II Ϫ/Ϫ IV Ϫ/Ϫ mice may be a consequence of malformation of thalamocortical and corticothalamic fibers providing major excitatory input into the Rt. Indeed, apoptotic death of Rt neurons could be induced by lesioning corticothalamic fibers on whole-brain slice cultures. We therefore propose that anterograde transneuronal degeneration of the Rt in polysialylation-deficient, NCAM-positive mice is caused by defective afferent innervation attributable to thalamocortical pathfinding defects.

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Spatiotemporal patterns of ontogenetic expression of parvalbumin in the superior colliculi of rats and rabbits

Cited by 14 publications

References 83 publications

Calbindin D28k and parvalbumin immunoreactivity in the rabbit superior colliculus: An anatomical study

Calbindin D28k and parvalbumin immunoreactivity in the rabbit superior colliculus: An anatomical study

The superior colliculus of the camel: a neuronal‐specific nuclear protein (NeuN) and neuropeptide study

Thalamocortical Pathfinding Defects Precede Degeneration of the Reticular Thalamic Nucleus in Polysialic Acid-Deficient Mice

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