Specific chiroptical sensing of cysteine via ultrasound-assisted formation of disulfide bonds in aqueous solution

Background: New amino derivatives of NBD type are of high interest due to their strong fluorescence, while compounds containing a disulphide moiety are of high interest in nano-chemistry due to their easiness of attaching to noble nanoparticles. Therefore, in this work a new fluorescent derivative of NBD and cystamine was obtained. Methods: The reaction between cystamine and NBD-chloride occurs straightforwardly, and the isolated new compound was characterized by IR, UV-Vis, fluorescence, 1H- and 13C-NMR, MS, etc. Results: Structural analysis confirmed the proposed structure and highlighted the fluorescence behavior. Conclusions: A new fluorescent derivative of cystamine was obtained and characterized by different means.

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N,N-Bis(7-nitrobenz[c][1,2,5]oxadiazol-4-yl)cystamine

Matei¹,

Culiță²,

Tecuceanu

et al. 2022

Molbank

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Specific chiroptical sensing of cysteine via ultrasound-assisted formation of disulfide bonds in aqueous solution

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N,N-Bis(7-nitrobenz[c][1,2,5]oxadiazol-4-yl)cystamine

N,N-Bis(7-nitrobenz[c][1,2,5]oxadiazol-4-yl)cystamine

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