Specific transport properties of medicinal chitosan films

Abstract

Processes of water vapor sorption by medicinal chitosan films and the kinetics of release of anti biotics of the cephalosporin series from these films have been studied. It has been found that the structural changes in the polymer matrix that are related particularly to its chemical modification via the interaction with drugs are the most probable cause of the deviation of the mass transfer mechanism from the classical Fick's mechanism.

The Effect of Different Chemical and Physical Processing on the Physicochemical and Functional Characterization of Chitosan Extracted from Shrimp Waste Species of Indian White Shrimp

“…Measurements of L * (lightness), a * (greenness-redness), b * (yellowness), total color difference (ΔE) and whiteness index (WI) were calculated using Eqs. (6) and (7) respectively [21].…”

“…Chitosan, ß-(1 → 4) D-glucosamine, is a cationic amino polysaccharide which is a partly deacetylated form of chitin (extracting from the waste of exoskeleton of shrimp) [5]. Chitosan has been interested in medicine, pharmaceutical, biomedical, biological, agriculture, environment and in food technology such as, food formulations, binding, thickening, gelling, stabilizing, clarifying, antimicrobial and antioxidant agent [6][7][8]. Over the years from 1936 until now, various procedures have been applied to extract chitin and the roles of various factors were considered in functional properties of chitosan, but here we focus on the extraction basis of the processes for industrial production of chitosan [9][10][11][12].…”

http://science2016.lp.edu.ua/chcht/mutual-activation-and-sorption-ability-rare-cross-linked-networks-intergel-system-based

“…Earlier, in works [25][26] we studied polymeric film systems based on ChT with a molecular mass of M sd = 334000 Da. The films received from a high-molecular sample of ChT were dissolved in water rather slowly and during the experiment they changed the initial weight no more than by 3-5 % (Fig.…”

Enzymatic Destruction of Film Materials on the Basis of Chitosan in the Presence of Cephalosporin Series Antibiotics

“…The exact area of a film sample, which is necessary for calculation of с s was determined on the data basis of an electronic scanning microscopy [20,21].…”