Speckle tracking echocardiography could detect the difference of pressure overload-induced myocardial remodelling between young and adult rats

Niu, Pei; Li, Li; Yin, Zhongjie; Du, Jie; Tan, Wenchang; Huo, Yunlong

doi:10.1098/rsif.2019.0808

“…CMR Analysis: The analysis was performed o ine by two experienced radiologists. Infarct size, edema, MVO and IMH were quanti ed by using the CVI 42 software (Circle Cardiovascular Imaging Calgary, Canada) (13). CMR feature tracking strains (GLS, GCS and GRS: global longitudinal, circumferential and radial strains), left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV) and left ventricular ejection fraction (LVEF) were determined by using the TomTec Imaging Systems (2D CPA MR, Cardiac Performance Analysis, Version 1.1.2, TomTec Imaging Systems, Germany) (14, 15).…”

Section: Methodsmentioning

confidence: 99%

Cardiac Strains for Prediction of Adverse Events and Ventricular Remodeling

Gong

¹

,

Lu

²

,

Huo

³

et al. 2020

Preprint

1

0

View full text Add to dashboard Cite

Background: Cardiac strains were assumed to accurately predict adverse events after acute ST-segment elevation myocardial infarction (STEMI). There are, however, some debates on it. The aim of the study was to evaluate the effects of cardiac strains obtained from cardiac magnetic resonance (CMR) on cardiac events and adverse LV remodeling.Methods: A prospective and two-center study included STEMI patients treated with primary PCI with implantation of stents. They underwent CMR before discharge. Major adverse cardiac events and LV remodeling were obtained during 6 months follow-up.Results: Between February 2015 and September 2016, 76 patients were available for the final analysis. We reported major adverse cardiac events (MACE) rate 23.7% using cardiac death, reinfarction, unplanned revascularization and heart failure as combined events in 6 months follow-up. Global longitudinal strain (GLS) can predict MACE independently, with OR=1.229 (1.087-1.390) and P=0.001. Moreover, GLS can predict LV remodeling independently, with OR=1.943 (1.133-3.334) and P=0.016.Conclusion: In patients with STEMI treated with primary PCI, CMR-determined GLS before discharge is a good predictor of MACE and adverse LV remodeling in 6 months follow-up.

show abstract

“…CMR Imaging Analysis: The analysis was performed o ine by two experienced radiologists. Infarct size, edema, MVO, and intramyocardial hemorrhage were quanti ed using CVI 42 software (Circle Cardiovascular Imaging Calgary, Canada) (13). CMR-FT strains (GLS, global circumferential strain (GCS), and global radial strain (GRS), LV end-diastolic volume (LVEDV), LV end-systolic volume, and LV ejection fraction (LVEF) were determined using the TomTec Imaging System (2D CPA MR, Cardiac Performance Analysis, version 1.1.2, TomTec Imaging Systems, Germany) (14,15).…”

Section: Methodsmentioning

confidence: 99%

Cardiac Strain as a Predictor of Adverse Events and Ventricular Remodeling: A Cohort Study

Gong

¹

,

Lü²,

Huo

³

et al. 2020

Preprint

0

View full text Add to dashboard Cite

Background: It remains controversial whether cardiac strain accurately predicts adverse events after acute ST-segment elevation myocardial infarction (STEMI). The aim of the present study was to evaluate the effects of cardiac strain revealed on cardiac magnetic resonance (CMR) imaging on cardiac events and adverse left ventricular (LV) remodeling.Methods: Between February 2015 and September 2016, we conducted a prospective two-center cohort study of patients with STEMI treated with primary percutaneous coronary intervention comprising stent implantation. All included patients underwent CMR imaging before discharge. Major adverse cardiac events (MACE) and LV remodeling were assessed during 6 months of follow-up.Results: Seventy-six patients were available for the final analysis. The MACE rate was 23.7%, using cardiac death, reinfarction, unplanned revascularization, and heart failure as combined events during 6 months of follow-up. The global longitudinal strain (GLS) was an independent predictor of MACE (OR=1.21 (1.07–1.36), P=0.002) and LV remodeling (OR=2.06 (1.14–3.73), P=0.017).Conclusion: In patients with STEMI treated with primary percutaneous coronary intervention, the GLS determined on CMR imaging performed before discharge is a predictor of MACE and adverse LV remodeling during 6 months of follow-up.

show abstract

“…CMR Imaging Analysis: The analysis was performed o ine by two experienced radiologists. Infarct size, edema, MVO, and intramyocardial hemorrhage were quanti ed using CVI 42 software (Circle Cardiovascular Imaging Calgary, Canada) (13). CMR-FT strains (GLS, global circumferential strain (GCS), and global radial strain (GRS), LV end-diastolic volume (LVEDV), LV end-systolic volume, and LV ejection fraction (LVEF) were determined using the TomTec Imaging System (2D CPA MR, Cardiac Performance Analysis, version 1.1.2, TomTec Imaging Systems, Germany) (14,15).…”

Section: Methodsmentioning

confidence: 99%

Cardiac Strain as a Predictor of Adverse Events and Ventricular Remodeling: A Cohort Study

Gong

¹

,

Lu²,

Huo

³

et al. 2020

Preprint

0

View full text Add to dashboard Cite

Background: It remains controversial whether cardiac strain accurately predicts adverse events after acute ST-segment elevation myocardial infarction (STEMI). The aim of the present study was to evaluate the effects of cardiac strain revealed on cardiac magnetic resonance (CMR) imaging on cardiac events and adverse left ventricular (LV) remodeling.Methods: Between February 2015 and September 2016, we conducted a prospective two-center cohort study of patients with STEMI treated with primary percutaneous coronary intervention comprising stent implantation. All included patients underwent CMR imaging before discharge. Major adverse cardiac events (MACE) and LV remodeling were assessed during 6 months of follow-up.Results: Seventy-six patients were available for the final analysis. The MACE rate was 23.7%, using cardiac death, reinfarction, unplanned revascularization, and heart failure as combined events during 6 months of follow-up. The global longitudinal strain (GLS) was an independent predictor of MACE (OR=1.21 (1.07–1.36), P=0.002) and LV remodeling (OR=2.06 (1.14–3.73), P=0.017).Conclusion: In patients with STEMI treated with primary percutaneous coronary intervention, the GLS determined on CMR imaging performed before discharge is a predictor of MACE and adverse LV remodeling during 6 months of follow-up.

show abstract

Speckle tracking echocardiography could detect the difference of pressure overload-induced myocardial remodelling between young and adult rats

Cited by 13 publications

References 62 publications

Cardiac Strains for Prediction of Adverse Events and Ventricular Remodeling

Cardiac Strains for Prediction of Adverse Events and Ventricular Remodeling

Cardiac Strain as a Predictor of Adverse Events and Ventricular Remodeling: A Cohort Study

Cardiac Strain as a Predictor of Adverse Events and Ventricular Remodeling: A Cohort Study

Contact Info

Product

Resources

About