Spectra of Antibacterial Activity of Propolis (Promax-C) Samples from Two Localities of Adamaoua Province (Cameroon)

Ethanol-extracted Cameroonian propolis exerts estrogenic effects and alleviates hot flushes in ovariectomized Wistar rats

“…It is well documented that phenolic compounds constitute the most numerous group of propolis components with respect to the quantity and type out of which flavonoids are the most abundant [40]. Many scientific reports on Cameroonian propolis corroborate this assertion and conclude that total polyphenols contents in Cameroonian propolis fall within the range of values reported for propolis from other countries [21, 24, 26, 27]. More precisely, Njintang et al [23] reported that the polyphenols content in PROMAX-C samples varied from 186 to 1084 mg/L.…”

“…Relation between phenolic compounds amount and antibacterial activity.[21, 24]Propolis Meiganga (2006)Methanol (3.7%)lup-20(29)-en-3-one, lupeol, erythrodiol palmitate, 18-iso-olean-12-ene-3,11-dione, Caffeic acid phenethyl ester (CAPE)Antinociceptive activity of all the three pentacyclic triterpenoids in the test models of chemical nociception and mechanical hypernociception[26]Propolis Meiganga (2008)Hexane (44.8%)Alkaloids, Coumarins, Steroids, Triterpenes, Volatile, 2 compound was not yet elucidatedAbsence of antibacterial activity[27]Propolis Meiganga (2008)Methanol (3.5%)Alkaloids, Reducing compounds, Coumarins, Flavonoids, Saponins, TanninsAntibacterial activities; It was active against Escherichia coli and Pseudomonas aeruginosa (MIC: 0.2 mg/ml)[27]Propolis Adamawa (2013)Acetone and methanol (70%)Terpenoids, phenolic acids, ursolic acid, β-amyrin, Prenylated phloroglucinone, cycloartenol acetatePhlorogucinonone was found to possess the highest potency against Trypanosoma brucei brucei [52]Propolis Adamawa (2007)Ethanol (missing data)Missing dataAmong all African propolis sample tested, Cameroonian propolis was the most potent.[25]Propolis Ngaoundal (2011)Ethanol (5.25%), methanol (9%) and water (1.5%)Volatile oils, Phenolic compounds, Saponins, Reducing substances, Coumarines, Flavonoids, Triterpenes, Catechic tannins, Fatty acids.All extracts contain phenolic compounds and present antiradical activities Antioxidant capacities: the order of decreasing antiradical activity is Water > Methanol > Ethanol[26]Propolis Ngaoundere (2004)Ethanol (missing data)Total polyphenols (mg/L) 10.99 ± 2.56; Tannins (mg/L): 1.57 ± 1.62The Cameroonians propolis exhibited higher scavenging (antiradical activity (%):83.4 ± 2.3); activity which could justify their commercialisation and role in the management of some chronic diseases[23]Propolis Ngaoundere (2003)Ethanol (missing data)Total polyphenols (mg/L) 227.8 ± 36.0; Tannins (mg/L): 16.3 ± 12.6 (PROMAX-C, 2003)Total polyphenols (mg/L) 772.8 ± 270.2; Tannins (mg/L): 453.8 ± 361.5 in PROMAX-C of 2006All PROMAX-C samples tested showed evidence of radical scavenging properties with values ranging from 28 to 70%. Radical scavenging activity: Antiradical activity (%):43.7 ± 13.8 for PROMAX-C made in 2003 and Antiradical activity (%):67.3 ± 3.0 for PROMAX-C made in 2006.[23]PropolisMeiganga (2005)Ethanol (4%)Contains phenolic compoundsAntibacterial activity against gram positive bacterial strain tested except Enterococcus faecalis […”

“…Radical scavenging activity: Antiradical activity (%):43.7 ± 13.8 for PROMAX-C made in 2003 and Antiradical activity (%):67.3 ± 3.0 for PROMAX-C made in 2006.[23]PropolisMeiganga (2005)Ethanol (4%)Contains phenolic compoundsAntibacterial activity against gram positive bacterial strain tested except Enterococcus faecalis [21]PropolisMartap (2005)Ethanol (3.5%)Most active than PROMAX-C from Meiganga with a most higher phenolic contentAntibacterial activity against gram positive bacterial strain tested except Enterococcus faecalis . This propolis was the most active and content more phenolic compounds than other tested propolis.[21] …”

Characterisation of triterpenes and new phenolic lipids in Cameroonian propolis

“…Much less is known, however, about the exact chemical constituents of African propolis. In Cameroon, propolis is an important traditional medicine which has antibacterial and antiradical activity (Njintang Yanou et al, 2012;Mbawala et al, 2009Mbawala et al, , 2010Talla et al, 2013). We carried out a phytochemical analysis of a propolis sample collected in North-Western Cameroon and report herein the characterisation of nine triterpenes, thirteen alk(en)ylphenols and nine alk(en)ylresorcinols.…”

Anti-Inflammatory and Analgesic Effect of Arachic Acid Ethyl Ester Isolated from Propolis

“…Propolis is a crude compound of beehive made by bees from resin harvest to several plants [5]. It is used in folk medicine as antibiotic [6], antiviral [7], antioxidant [5], and anti-inflammatory [8]. The present study was undertaken to evaluate the antiinflammatory and analgesic activities of arachic acid ethyl ester (AAEE) isolated from propolis in rats.…”