Spectral Beam Shaping in Unenhanced Chest CT Examinations

Suntharalingam, Saravanabavaan; Allmendinger, Thomas; Blex, Sebastian; Al-Bayati, Mohammad; Naßenstein, Kai; Schweiger, Bernd; Forsting, Michael; Wetter, Axel

doi:10.1016/j.acra.2017.08.011

Cited by 13 publications

(6 citation statements)

References 18 publications

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“…Also, spectral shaping was considered to allow for substantial radiation dose reduction for adult chest CT in phantom studies. 6 However, Messerli et al 13 found that the sensitivity for small PN detection decreases to 91% at ultralow-dose levels with tin prefiltration (0.13 mSv) compared with 100% in the reference protocol (1.8 mSv) in a study design with intraindividual double exposure. Other studies analyzed the influence of advanced iterative model reconstructions compared with hybrid iterative reconstructions to detect PNs.…”

Section: Discussionmentioning

confidence: 99%

“…4 Moreover, spectral shaping of the x-ray beam by tin prefiltration can minimize the radiation dose below the conventional limits and increase spatial resolution. 5,6 The lowest submillisievert dose levels, comparable to radiographs in 2 planes, are possible using these techniques. 7 Saltybaeva et al 8 were able to prove that these protocols 9 can also substantially reduce the risk for de novo induction of lung cancer to 0.35 per 100,000 cases, which is especially important for repetitive examinations in large patient collectives.…”

mentioning

confidence: 99%

“…Improved detector technology with high photon efficiency can decrease the radiation dose by 60% to 80% 4 . Moreover, spectral shaping of the x-ray beam by tin prefiltration can minimize the radiation dose below the conventional limits and increase spatial resolution 5,6 . The lowest submillisievert dose levels, comparable to radiographs in 2 planes, are possible using these techniques 7 .…”

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confidence: 99%

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Personalized Chest Computed Tomography

et al. 2021

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Objectives The purpose of this study was to evaluate the minimum diagnostic radiation dose level for the detection of high-resolution (HR) lung structures, pulmonary nodules (PNs), and infectious diseases (IDs). Materials and Methods A preclinical chest computed tomography (CT) trial was performed with a human cadaver without known lung disease with incremental radiation dose using tin filter-based spectral shaping protocols. A subset of protocols for full diagnostic evaluation of HR, PN, and ID structures was translated to clinical routine. Also, a minimum diagnostic radiation dose protocol was defined (MIN). These protocols were prospectively applied over 5 months in the clinical routine under consideration of the individual clinical indication. We compared radiation dose parameters, objective and subjective image quality (IQ). Results The HR protocol was performed in 38 patients (43%), PN in 21 patients (24%), ID in 20 patients (23%), and MIN in 9 patients (10%). Radiation dose differed significantly among HR, PN, and ID (5.4, 1.2, and 0.6 mGy, respectively; P < 0.001). Differences between ID and MIN (0.2 mGy) were not significant ( P = 0.262). Dose-normalized contrast-to-noise ratio was comparable among all groups ( P = 0.087). Overall IQ was perfect for the HR protocol (median, 5.0) and decreased for PN (4.5), ID-CT (4.3), and MIN-CT (2.5). The delineation of disease-specific findings was high in all dedicated protocols (HR, 5.0; PN, 5.0; ID, 4.5). The MIN protocol had borderline IQ for PN and ID lesions but was insufficient for HR structures. The dose reductions were 78% (PN), 89% (ID), and 97% (MIN) compared with the HR protocols. Conclusions Personalized chest CT tailored to the clinical indications leads to substantial dose reduction without reducing interpretability. More than 50% of patients can benefit from such individual adaptation in a clinical routine setting. Personalized radiation dose adjustments with validated diagnostic IQ are especially preferable for evaluating ID and PN lesions.

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Section: Discussionmentioning

confidence: 99%

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Personalized Chest Computed Tomography

et al. 2021

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“…5 Energy spectrum purification technology, Sn100 kVp, has weak penetration, which is suitable for scanning the lungs. 6,7 Therefore, this study discusses the image quality and dose of radiation from CTPA under the Sn100 kVp tube voltage mode to provide reference information for its future clinical application.…”

Section: Introductionmentioning

confidence: 99%

Effects of the Sn100 kVp Tube Voltage Mode on the Radiation Dose and Image Quality of Dual-Source Computed Tomography Pulmonary Angiography

Zhang¹,

Liu²,

Jia³

et al. 2021

IJGM

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Objective This study aimed to investigate the effects of the Sn100 kVp tube voltage mode on the image quality and radiation dose of computed tomography pulmonary angiography (CTPA). Methods A total of 145 patients who underwent CTPA were randomly divided into five groups: control group (120 kVp, 150 mAs), test group A (Sn100 kVp, 270 mAs), test group B (120 kVp, 30 mAs), test group C (70 kVp, 150 mAs), and test group D (80 kVp, 70 mAs). After image post-processing, the image quality and radiation dose of each group were analyzed. Results The computed tomography values of images in the four test groups were more than 250 HU, which met the criteria for diagnosis. The signal-to-noise ratio and contrast-to-noise ratio of the images in the four test groups were lower than those in the control group. The radiation dose in each test group was lower than in the control group. The radiation dose was lowest in test group A. Conclusion The Sn100 kVp energy spectrum purification protocol can meet the requirements for clinical diagnosis, ensure image quality, and reduce the dose of radiation that patients receive.

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“…Leschka et al [17] found that applying tin filters in dualenergy CT leads to improved sensitivity and specificity for the differentiation of renal cysts from the improvement of the solid mass in a kidney phantom model. Also, Suntharalingam et al [18] have shown in their phantom study that unimproved thoracic CT executed at 100 kVp or 150 kVp with tin filtration allows a reduction in the adult radiation dose, but not in children and neonates. Then, they have proposed a tube voltage between 70 and 110 kVp for the tested radiation dose.…”

Section: Introductionmentioning

confidence: 99%

Band pass filter plan in fluoroscopy for high energy range

et al. 2019

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In fluoroscopy, the absorption edge, the energy range, and the X-ray spectrum peak are the most important factors in filtration to obtain a proper image. Here, an experimental study was conducted to determine the filters that remove low-energy spectrums and attenuate high-energy ranges so that they cannot fundamentally affect image quality and diminish the absorbed dose by the patient. Considering the attenuation curves of proper elements besides accessibility and productivity issues, three elements were investigated that comprised Copper, Lead and Tin with diverse thicknesses in the X-ray energy range of 100 to 125 keV. Also, a simulation study by Monte Carlo N-Particle code was performed with an accuracy of 99%. The findings demonstrated that the use of a 0.1 mm lead filter retains the best image quality along with a significant reduction in the dose ratio obtained by raising milliampere. Multi or auxiliary filters require additional testing to achieve better image quality. In order to obtain the best possible X-ray band pass spectrum, the analysis of the attenuation and absorption profiles of the various elements plays an essential role in the calculation of the output intensities.

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Spectral Beam Shaping in Unenhanced Chest CT Examinations

Cited by 13 publications

References 18 publications

Personalized Chest Computed Tomography

Personalized Chest Computed Tomography

Effects of the Sn100 kVp Tube Voltage Mode on the Radiation Dose and Image Quality of Dual-Source Computed Tomography Pulmonary Angiography

Band pass filter plan in fluoroscopy for high energy range

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