Spectrofluorimetric determination of the anti‐Covid 19 agent, remdesivir, in vials and spiked human plasma

Abstract

Following the sudden widespread of the novel coronavirus (COVID-19) which first appeared in Wuhan city. Remdesivir (REM) was the first medicine licensed by the US Food and Drug Administration (FDA) for COVID-19 infected hospitalized patients.Hence, there was an urgent demand for the optimization of efficient selective and sensitive methods to be developed for the determination of REM in pharmaceuticals as well as biological samples. A sensitive and simple green spectrofluorimetric

Recent analytical methodologies for the determination of anti-covid-19 drug therapies in various matrices: a critical review

“…Moreover, Noureldeen et al have studied the possibility of using the established methods in quality control laboratories. 38…”

“…Moreover, Noureldeen et al have studied the possibility of using the established methods in quality control laboratories. 38 Table 1 and 2 summarizes the measurement conditions of the various analytical methods applied in the quantication of RMD in pharmaceutical dosage forms and biological matrices, respectively.…”

The first spectrofluorimetric protocol for sensitive quantitative analysis of bromocriptine in its pure and pharmaceutical forms: evaluation of the greenness of the method

“…In the current study, the ecoscale score was used to assess how environmentally friendly the proposed approach is. [23][24][25] This can be determined by giving points to each component in the method. The outcome of the analytical eco-scale evaluation is represented with a number which is calculated by subtracting penalty points from 100.…”

Chromatographic analysis of bromhexine and oxytetracycline residues in milk as a drug analysis medium with greenness profile appraisal

“…Nowadays, the use of green analytical chemistry is considered essential in order to protect the environment and individuals by replacing harmful solvents with greener ones. 35,36 Furthermore, the greenness prole of the methods was evaluated using ve metrics, and the results conrmed the superiority of these methods in terms of health and environmental impacts as well as the performance of the methods.…”