Spectrophotometric Skin Measurements Correlate with EORTC/RTOG-Common Toxicity Criteria

Abstract

For classification of acute radiation toxicity there seems to be no need to replace the common CTC scoring by technical methods.

Objective Assessment of Dermatitis Following Post-operative Radiotherapy in Patients with Breast Cancer Treated with Breast-conserving Treatment

“…Momm et al reported that the skin color (especially red, the a* value) depended on the radiation dose applied to the skin and that the objective spectrophotometric measurements correlated well with the subjective CTC scores [14]. They concluded that for classification of acute radiation toxicity there seems to be no need to replace the common CTC scoring with technically more sophisticated methods.…”

“…In most previous studies, the extent of erythema was determined with subjective means, such as visual inspection. Some attempts to establish objective measurements have been reported in the literature [4,11,12,14,21,22], i.e., visual reflectance spectroscopy and determination of a high-frequency dielectric constant [15]. These results have prompted the present study, which is concerned with the development of an objective assessment method for skin reaction that can be used by multiple observers, especially when a multi-institute trial is involved.…”

Longitudinal practical measurement of skin color and moisture during and after breast-conserving therapy: influence of neoadjuvant systemic therapy

“…We therefore conducted the present study to examine the radiation dermatitis following radiotherapy in patients who underwent NST and control group. In addition, as several objective assessments tools have been used because of their reliance and reproducibility in the areas of dermatology and other fi elds including radiology, [4][5][6][7][8][9] we included them in this study and examined radiation dermatitis by objective methods.…”

Spectrophotometer and ultrasound evaluation of late toxicity following breast-cancer radiotherapy

“…[7][8][9] Based on clinical exam findings, physicians assigned a grade from 0 (absent) to 4 (severe). Skin toxicity is primarily evaluated by visual inspection based on changes in color (usually melanin), while subcutaneoustissue toxicity is primarily evaluated by palpation.…”