Spectroscopic Characterisation of Metal Complexes with Tetradentate Ligand

Kumar, Sahdeo; Pandey, Pinki; Sinha, Navneet; Chaudhari, Sudama; Sharma, Sandeep

doi:10.21315/jps2018.29.3.1

Cited by 6 publications

(4 citation statements)

References 15 publications

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“…Mn(II) and Co(II) complexes are 5.84 and 4.90 B.M, this indicates high-spin. Mn(II) and Co(II) ions have five and three unpaired electrons in each compound’s respective outer valence shell [ 25 , 26 ]. The magnetic moment of the Cu(II) complex was 1.72 BM, which is consistent with an octahedral shape and one unpaired electron [ 27 ].…”

Section: Resultsmentioning

confidence: 99%

Physico-Chemical Study of Mn(II), Co(II), Cu(II), Cr(III), and Pd(II) Complexes with Schiff-Base and Aminopyrimidyl Derivatives and Anti-Cancer, Antioxidant, Antimicrobial Applications

2023

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A new class of biologically active mineral complexes was synthesized by reacting the following metal salts: MnCl2·4H2O, CoCl2·6H2O, CuCl2·2H2O, CrCl3·6H2O, and PdCl2 respectively with 2-amino-4,6-dimethyl pyrimidine (ADMPY) and Schiff’s base resulting from the condensation reaction between benzaldehyde with p-phenylenediamine and 2-hydroxy-1-naphthaldehyde as ligands have been synthesized and characterized on the basis of their CHN, thermal analysis, XRD, SEM and magnetic measurements along with their FT-IR and UV-vis spectra. The scanning electron microscope SEM measurements and the calculations on the powder XRD data indicate the nano-sized nature of the prepared complexes (average size 32–88 nm). The spectral data confirmed the coordinated ligand (HL) via a nitrogen atom of an azomethine group (-C=N-) and phenolic -OH group and NH2-ADMPY ligand with the metal ions. An octahedral geometry for all complexes has been proposed based on magnetic and electronic spectral data except Pd(II) complex, which has a tetrahedral geometry. Molecular modeling was performed for Cu(II) complex using the density functional method DFT/B3LYP to study the structures and the frontier molecular orbitals (HOMO and LUMO). The antioxidant of the complexes was studied using the 2,2-diphenyl-1-picrylhydrazyl (DPPH)-free radical-scavenging assays. The metal complexes were tested in vitro for anticancer activities against two cancer lines A-549 and MRC-5 cells. Cu(II) and Pd(II) complexes showed the highest cytotoxicity effect, comparable to that of other cis-platinum-based drugs. The complexes showed significant activity against fungi and bacteria.

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Section: Resultsmentioning

confidence: 99%

Physico-Chemical Study of Mn(II), Co(II), Cu(II), Cr(III), and Pd(II) Complexes with Schiff-Base and Aminopyrimidyl Derivatives and Anti-Cancer, Antioxidant, Antimicrobial Applications

2023

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“…As for the Cu(II) complex, the analysis exhibited two principal bands centered at 27.548 and 35.211 nm, referring to both n→π* and π→π*. The different characteristic bands of Mn(II), Fe(III), Ni(II), and Cu(II) complexes appearing in the visible region have been assigned to d-d transitions typical of octahedral metal complexes [45,46].…”

Section: Uv-vis Spectrophotometric Analysismentioning

confidence: 92%

Synthesis and Characterization of a New Alginate/Carrageenan Crosslinked Biopolymer and Study of the Antibacterial, Antioxidant, and Anticancer Performance of Its Mn(II), Fe(III), Ni(II), and Cu(II) Polymeric Complexes

EL-Ghoul,

Al-Fakeh,

Al-Subaie

2023

Polymers

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Natural polysaccharides are essential to a wide range of fields, including medicine, food, and cosmetics, for their various physiochemical and biological properties. However, they still have adverse effects limiting their further applications. Consequently, possible structural modifications should be carried out on the polysaccharides for their valorization. Recently, polysaccharides complexed with metal ions have been reported to enhance their bioactivities. In this paper, we synthesized a new crosslinked biopolymer based on sodium alginate (AG) and carrageenan (CAR) polysaccharides. The biopolymer was then exploited to form complexes with different metal salts including MnCl2·4H2O, FeCl3·6H2O, NiCl2·6H2O, and CuCl2·2H2O. The four polymeric complexes were characterized by Fourier-transform infrared spectroscopy (FT-IR), elemental analysis, ultraviolet–visible spectroscopy (UV–Vis), magnetic susceptibility, molar conductivity methods, and thermogravimetric analysis. The X-ray crystal structure of the Mn(II) complex is tetrahedral and belongs to the monoclinic crystal system with the space group P121/n1. The Fe(III) complex is octahedral and crystal data fit with the cubic crystal system with the space group Pm-3m. The Ni(II) complex is tetrahedral and crystal data correspond to the cubic crystal arrangement with the space group Pm-3m. The data estimated for the Cu(II) polymeric complex revealed that it is tetrahedral and belongs to the cubic system with the space group Fm-3m. The antibacterial study showed significant activity of all the complexes against both Gram-positive bacteria (Staphylococcus aureus and Micrococcus luteus) and Gram-negative (Escherichia coli and Salmonella typhimurium) pathogenic strains. Similarly, the various complexes revealed an antifungal activity against Candida albicans. The Cu(II) polymeric complex recorded a higher antimicrobial activity with an inhibitory zone reaching 4.5 cm against Staphylococcus aureus bacteria and the best antifungal effect of 4 cm. Furthermore, higher antioxidant values of the four complexes were obtained with DPPH scavenging activity varying from 73 to 94%. The two more biologically effective complexes were then selected for the viability cell assessments and in vitro anticancer assays. The polymeric complexes revealed excellent cytocompatibility with normal human breast epithelial cells (MCF10A) and a high anticancer potential with human breast cancer cells (MCF-7) which increase significantly in a dose-dependent manner.

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“…The thermal decomposition of compounds 1-3 В спектрах дифузного відбиття сполук 1-3 відзначено дві смуги, які відповідають наступним переходам: 4 T 1g (F)→ 4 T 2g (1 -7250, 2 -7100, 3 -7300 см -1 ), 4 T 1g (F)→ 4 T 1g (P) (1 -13800, 2 -14200, 3 -14000 см -1 ). Це однозначно вказує на реалізацію октаедричної конфігурації поліедру кобальту [13,14].…”

Section: Tableunclassified

DOUBLE Ge(IV)-Co(ІІ) COMPLEXES WITH 1-HYDROXYETHYLIDENEDIPHOSPHONIC ACID AND 2,2-BIPYRIDINE

Martsinko¹,

Seifullina²

2022

Вісник ОНУ

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The novel developed synthesis methods allowed to obtain three Ge(IV)-Co(II) coordination compounds with 1- hydroxyethylidenediphosphonic acid and 2,2`-bipyridine [{Co(bipy)3}2{Co(bipy)(H2O)4}2][{Ge(μ-OH)(μ-hedp)}6Cl2]∙2H2O (1), [Co(bipy)3]4[{Ge(μ-OH)(μ-hedp)}6Cl2]∙30H2O (2), [Co(bipy)3]3[{Ge(μ-OH)(μ-hedp)}6]⋅20Н2О⋅2CH3COOH (3). Complexes are characterized by the methods of elemental analysis, IR-, Diffuse Reflectance spectroscopy, thermogravimetric analysis. All absorption bands presented in the IR-spectra of compounds 1-3 are highlighted in the Table 2. Absorption bands of the P-O bond are detected at ~1053 and ~970 сm-1, that indicates the presence of the fully deprotonated PO32- groups in the composition of complexes. Furthermore, n(OH), ν(Ge–Ophosph), d(Ge–OH) bands characteristic for all the previously synthesized compounds with [Ge6(m-OH)6(m-hedp)6]6-anion is detected in the IR spectra of 1-3. Presence of the crystal water molecules is confirmed by the ν(OH) at 3400 сm-1. A set of the bands usual for the aromatic molecules (n(C–Harom), n(C–Carom), das(CH3), ds(CH3), n(С–N)) is assigned with 2,2`-bipyridine in the structure of all compounds. A special feature of the IR-spectra of 1 is presence of COOH absorption band at 1700 сm-1, that indicates the location of solvated acetic acid. Complex 1 also contains coordination water molecules, confirmed by the d(H2O) at 1642 сm-1 in its IR-spectrum. Absorption bands of Co–N and Со-О bonds evidence that 2,2`-bipyridine and H2O molecules are coordinated to the cobalt atom. Thermal decomposition of 1-3 differs a lot. Variable interval and temperature of the first endoeffect is explained by the different nature of water in them – crystal (1-3) and coordinated (1). In the diffuse reflection spectra of compounds 1-3, two bands corresponding to the following transitions are observed: 4T1g(F)→ 4T2g (1 – 7250, 2 – 7100, 3 – 7300 сm-1), 4T1g(F)→ 4T1g(P) (1 – 13800, 2 – 14200, 3 – 14000 сm-1). Such results confirm an octahedral configuration of cobalt atom. There was also established, how composition and structure of the synthesized compounds depend from the molar ratio of the reagents and anion of the initial Co(II) salt (chloride, acetate).

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Spectroscopic Characterisation of Metal Complexes with Tetradentate Ligand

Cited by 6 publications

References 15 publications

Physico-Chemical Study of Mn(II), Co(II), Cu(II), Cr(III), and Pd(II) Complexes with Schiff-Base and Aminopyrimidyl Derivatives and Anti-Cancer, Antioxidant, Antimicrobial Applications

Physico-Chemical Study of Mn(II), Co(II), Cu(II), Cr(III), and Pd(II) Complexes with Schiff-Base and Aminopyrimidyl Derivatives and Anti-Cancer, Antioxidant, Antimicrobial Applications

Synthesis and Characterization of a New Alginate/Carrageenan Crosslinked Biopolymer and Study of the Antibacterial, Antioxidant, and Anticancer Performance of Its Mn(II), Fe(III), Ni(II), and Cu(II) Polymeric Complexes

DOUBLE Ge(IV)-Co(ІІ) COMPLEXES WITH 1-HYDROXYETHYLIDENEDIPHOSPHONIC ACID AND 2,2-BIPYRIDINE

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