Spectroscopic studies, structure simulation and phenol binding property of dimetallocyclophanes derived from tetradentate Schiff bases

Metal Cu(II) and Zn(II) bipyridyls as inhibitors of lactate dehydrogenase

“…Following the method reported earlier (Mishra et al 2004a), Cu(II) acetate dihydrate (2.17 g, 1 mmol) and Zn(II) acetate dihydrate (2.2 g, 1 mmol) were added separately to the solution of 2,2 0 bipyridine (1.56 g, 1 mmol) in 20 ml methanol with constant stirring up to 4 h. The resultant solids were filtered, washed with methanol and analyzed on IR and 1 H-NMR (for Zn only).…”

“…To a fixed concentration of LDH (1 · 10 À6 M) prepared in methanol:water (1:1) mixture, increasing concentration of both the complexes (1 · 10 À6 -1 · 10 À8 M), prepared in the same solvent, were incubated separately for 30 min at room temperature followed by measurement of optical density at 200-800 nm. To calculate association constant (Kc) between the complexes and LDH, differences in OD observed between the untreated and treated samples at 280 nm were tested on Benesi-Hilde Brand (BH) equation (Mishra et al 2004a). The formulae adopted was…”

Studies on phenol-keto tautomerism, metal ion binding, and free radical scavenging properties of newly synthesized naphthalene-based tetraimine Schiff base

“…Schiff bases containing symmetrical structure (R-N=CH-Ar-CH=N-R or R-CH=N-Ar-N=CH-R) have been extensively synthesized [1][2][3] and used in coordination chemistry because of forming stable complexes with most transition metal ions easily [4][5] [19]. They can be utilized as catalysts [20], polymer stabilizers [21] and dyes [22].…”

“…In coordination chemistry, Schiff bases are well known as mono-, bi-and polydentate ligands. Schiff bases containing symmetrical structure (R-N=CH-Ar-CH=N-R or R-CH=N-Ar-N=CH-R) have been extensively synthesized [1][2][3] and used in coordination chemistry because of forming stable complexes with most transition metal ions easily [4][5]. Schiff bases and their metal complexes have been reported to show antifungal and antibacterial [6], antiproliferative [7], antitubercular [8], analgesic [9], antiviral [10], antipyretic [11], enzim inhibitory [12], antidiabetic [13], anticonvulsant [14], herbicidal [15], anticorrosion [16], and anti-HIV [17] activities.…”

Novel molecular architecture constructed on the skeleton of salen and salophen containing Zn(II) 2,2′-bipyridyl

“…Selection for 2,2 0 -bipyridine comes from the reports [9] that, bipyridyl containing complexes are exploited into self assembled systems and are found to dictate the stacking interactions besides their steric effects. Thus, based on these precedence, and in view of our earlier interest in metalSchiff base complexes [10], it was found worthwhile to exploit salen and salophen ligands with 2,2 0 -bipyridine attached zinc diacetate in anticipation to get novel supramolecular architecture of micrometer length.…”