We design a scheme of precoding matrices for two-way multiuser relay systems, where a multiantenna relay station (RS) operating in an amplify-and-forward model simultaneously receives information from all multiple-antenna users. Considering the feasibility in mathematical analysis, users are distributed in two symmetrical groups. To reduce the complexity of proposed precoding scheme, we employ the QR decomposition and complex lattice reduction (CLR) transform to replace the two times singular value decomposition (SVD) of conventional BD-based precoding algorithm by introducing a combined channel inversion to eliminate the multiple users interference (MUI). Simulation and performance analysis demonstrate that the proposed LR-MMSE algorithm has not only a better bit error rate (BER) performance, a higher sum-rate, and simple architecture, but also 89.8% and 35.5% less complexity compared to BD-and MMSE-based scheme.