Spectrum of intracranial tumours in a tertiary health care facility: our findings

Soyemi, Sunday Sokunle; Oyewole, Olugbenga

doi:10.11604/pamj.2015.20.24.4935

Cited by 14 publications

(26 citation statements)

References 10 publications

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“…17,18 Gliomas were the commonest tumour type, accounting for 38.2% of intracranial tumours followed closely by meningioma (36.2%). This is in keeping with findings in other studies 5,[7][8][9][10]17,18 Although gliomas are reported to be commoner in males, 3,5,7 there was a slight female preponderance in this study, which is similar to an earlier publication in Tema, Ghana by Andrews et al 12 This may be the true picture or just a trend suggesting that females tend to seek medical treatment more than men with similar conditions in Ghana.…”

Section: Discussionsupporting

confidence: 92%

“…The total number of intracranial tumours seen over the study period showed female preponderance (see Table 1) similar to the findings by Soyemi SS et al 8 This is shown to be statistically significant (p= 0.031) in Table 2.…”

Section: Discussionsupporting

confidence: 87%

“…Patterns of distribution of these tumours vary across the globe. [1][2][3][4][5][7][8][9][10]12,13,17,18 This study sought to determine the pattern of intracranial tumours in neurosurgical patients with intracranial tumours who presented at Korle Bu Teaching Hospital, Accra, Ghana for treatment between January 2010 and December 2015. 102 histologically diagnosed intracranial tumours out of 335 radiologically diagnosed intracranial tumours were included in the study.…”

Section: Discussionmentioning

confidence: 99%

“…Meningioma was commoner in females as reported in other studies. 2,4,5,[7][8][9][10][11]17,18 It is also worthy of note that pituitary adenoma, metastatic tumours and craniopharyngioma, which followed gliomas and meningiomas in that order, in terms of prevalence, were all slightly commoner in females. Glioblastoma and pilocytic astrocytoma were the commonest gliomas with the former commoner in the > 45 years' age group similar to the CBTRUS study, 2 and the latter in the under 16 years' age group.…”

Section: Discussionmentioning

confidence: 99%

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Pattern of intracranial tumours in a tertiary hospital in Ghana

Ekpene¹,

Ametefe²,

Akoto³

et al. 2017

Ghana Medical Journal

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Objective: This study seeks to describe the pattern of intracranial tumours in Korle Bu Teaching Hospital (KBTH) based on patient demographics, clinical presentation, spatial distribution of tumour and histological findings. Method: The study design is retrospective and descriptive. Data was obtained from the clinical records of patients with intracranial tumours treated in our neurosurgery unit between January 2010 to December 2015, and histology reports obtained from the histopathology unit. Patients with intracranial tumours without definitive histological diagnosis were excluded. Results: Of the 102 histologically diagnosed brain tumours, out of 335 brain tumour cases seen in the period under review, 58 (56.9%) were females and 44 (43.1%) were males (p = 0.031). Gliomas were the commonest intracranial tumours-39(38.2%) followed by Meningiomas 37(36.2%) and Pituitary Adenoma-9(8.8%). Astrocytoma was the commonest type of Glioma comprising 30(77%) of the 39 cases. Meningotheliomatous meningioma was the commonest type of meningioma with 11 (29.7%) of 37 cases. Of the 39 Gliomas 17(43.6%) were males and 22(56.4%) were females, while for the Meningioma 17(46%) were males and 20(54%) were females. The commonest symptom was headache (64%) and the commonest tumour location was supratentorial (77.5%). The crude incidence rate of intracranial tumours in this study was 1.34 per 100,000 populations per year. Conclusion: Gliomas are the commonest intracranial tumours seen in our series. Overall, females were more commonly affected than males in most brain tumours in this series, including both gliomas and meningiomas.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Pattern of intracranial tumours in a tertiary hospital in Ghana

Ekpene¹,

Ametefe²,

Akoto³

et al. 2017

Ghana Medical Journal

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“…Only four patients had a tumor volume ≤50 cm 3 , and among these cases, three were independent at 1 year. Tumor size above 101-500 cm 3 had the most significant impact on outcome with 58.8% of the patients in this group dead within 1 year (P = 0.009). Patients with tumor volume above 50 cm 3 accounted for 94% of the mortality.…”

Section: Sizementioning

confidence: 92%

The Challenges of Management of High-grade Gliomas in Nigeria

Ndubuisi

Mezue

Nzegwu

et al. 2017

Journal of Neurosciences in Rural Practice

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Background:High-grade gliomas (HGG) are among the most challenging brain tumors despite many research efforts worldwide.Aim:The aim of this study was to evaluate the local challenges that may influence outcome of HGG managed in a neurosurgical center in Nigeria.Methodology:Retrospective analysis of prospectively recorded data of patients managed for intracranial HGG at Memfys Hospital for Neurosurgery, Enugu, Nigeria, between the year 2006 and 2015. Only cases with conclusive histology following surgery were analyzed.Results:Glioma was 60 (23.8%) of 252 histology confirmed brain tumors. HGG represented 53.8% of gliomas with male:female ratio of 2.2:1.0 and peaked from fifth decade of life. Glioblastoma multiforme accounted for 69% of HGG. At 1-year postsurgery, 53% of HGGs were dead and 88% of these deaths were in the World Health Organization Grade IV group. Only 40% of cases could receive adjuvant treatment with only 15% mortality at 1 year in this subgroup that received adjuvant therapy. In addition, 19% of cases had surgery at Karnofsky score (Ks) of ≥70%. However, 94% of mortality at 1 year was related to surgery at Ks of ≤60%. Only four patients had a tumor volume of ≤50 cm3, and among these cases, three patients were independent at 1 year. Patients with tumor volume above 50 cm3 accounted for 94% of mortality.Conclusion:The peak age incidence for HGG seems to be lower than in Caucasians. Most cases present late with poor Ks and big tumor volume. The proportion with access to adjuvant treatment is still poor. Preoperative Karnofsky, extent of resection, duration of hospital, and Intensive Care Unit stay have impact on outcome.

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Histological types of brain tumors diagnosed at the Kenyatta National Hospital between 2016 and 2019: a retrospective study

Gesaka,

Okemwa,

Mwachaka

2024

Discov Onc

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Purpose To determine the histological types of brain tumors diagnosed at the Kenyatta National Hospital, Nairobi, Kenya. Methods This retrospective study retrieved patient-archived records at the Kenyatta National Hospital for the period 2016–2019. The histological types of brain tumors were assessed according to age, sex, and the WHO classification for CNS tumors using the GNU PSPP version 1.6.2-g78a33 software. Results were presented in tables and figures. Results During the study period, brain tumors appeared to increase gradually; however, there was a decline in 2018. During the study period, 345 brain tumor records were retrieved. Data on age were missing 33 records; hence, 312 records were included for age analyses. The mean age for the pediatrics and adults was 9 (± 5 SD) and 45 (± 14 SD) years, respectively. 88 (28.2%) and 224 (71.8%) tumors were diagnosed among pediatrics and adults, respectively. Most tumors, 60 (19.2%) were reported in patients aged ≤ 10 years, followed by 55 (17.6%), 48 (15.4%), and 47 (15.1%) in patients aged 31–40, 51–60, and 41–50, years, respectively. In both pediatrics and adults, most tumors were diagnosed in females aged ≤ 10 years and 31–40 years, respectively. Overall, two peaks were observed in patients aged 5–15 years and 40–45 years. Gliomas, 43 (48.9%) and medulloblastomas, 21 (23.9%) were the most common tumors in pediatrics, whereas meningiomas, 107 (47.8%) and gliomas, 70 (31.3%) were the most common tumors in adults. Most pediatric and adult tumors were benign with 50 (56.8%) and 157 (70.1%) cases, respectively. Low-grade gliomas and medulloblastomas were the commonest benign and malignant tumors among pediatrics, with 31 (62%) and 21 (55.3%) cases, respectively. Conversely, meningiomas and high-grade gliomas were the most common benign and malignant tumors in adults, with 106 (67.5%) and 44 (65.7%) cases, respectively. Conclusion This study highlights the existing burden of brain tumors in Kenya and data from KNH may be representative of the national burden of BTs. This study lays a foundation for subsequent clinical and epidemiological studies and emphasizes the need to adopt existing reporting standards to help realize a complete picture of the burden of brain tumors in Kenya.

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Spectrum of intracranial tumours in a tertiary health care facility: our findings

Cited by 14 publications

References 10 publications

Pattern of intracranial tumours in a tertiary hospital in Ghana

Pattern of intracranial tumours in a tertiary hospital in Ghana

The Challenges of Management of High-grade Gliomas in Nigeria

Histological types of brain tumors diagnosed at the Kenyatta National Hospital between 2016 and 2019: a retrospective study

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