Spectrum of Posterior Cranial Fossa Space Occupying Lesions- Our Experience at a Tertiary Care Centre

Gollapalli, Sri Lakshmi; Moula, Mohmed Chand; Shriram, Shriram; Kharidehal, Durga

doi:10.14260/jemds/2018/898

Cited by 3 publications

(1 citation statement)

References 14 publications

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“…(14) Similar studies done by Srilakshmi et al (21.8%) and Meenakshi Sundaram et al (60%) showed great variation in prevalence probably related to demographic attributes. (15,16) (14,15,16) Gender-wise distribution: Majority of the tumours in posterior Fossa had male predilection with M:F ratio of 1.6:1. except meningioma which favoured females with M:F ratio of 1:1.3. These findings are concordant with reference studies.…”

Section: Clinical Presentation Inmentioning

confidence: 99%

Clinicopathological spectrum of Intracranial Posterior Fossa Tumours and their Prognostic significance

Gubbala

Mattaparti

Bhavani³

2019

APALM

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Background: Intracranial Posterior fossa tumors are critical brain lesions with significant neurological morbidity and mortality due to limited space and involvement of vital brain stem nuclei and fourth ventricle. Early diagnosis of posterior fossa tumors is vital to prevent potential risks of Brain stem compression, herniation, hydrocephalus and death.Aim of the Study: 1. To study the morphological spectrum of intracranial posterior fossa SOLs. 2.To determine the frequency of posterior fossa SOLs reported in the tertiary care center of Nalgonda district. 3. To correlate clinical presentation with histopathological diagnosis and assess prognosis, and compare it with national and international literature.Materials and Methods: The present study was a retrospective description study conducted at the Department of pathology, Kamineni Institute of Medical Sciences, Narketpalli over a period of 3 years starting from June 2015 to June 2018. During this period, histopathological analysis of all the intracranial posterior cranial fossa tumors was done, correlated with clinical and radiological findings and prognosis assessed.Result: In our study Posterior fossa tumors are predominantly seen in adults with peak incidence in fourth decade. In children majority of the tumors were reported below 5 years of age. Most common presenting symptom was head ache and vomiting. Most common tumor was Medulloblastoma in children and Schwannoma in adults. Most common location was Cerebello-pontine angle followed by cerebellum. Recurrence rates were higher for CP angle tumors due to difficult sub-total resection. Prognosis is good for patients with total resection of tumors. Conclusion:Posterior fossa tumours are critical brain lesions with significant neurological morbidity and mortality. With rapid advancement in radiology and advent of modern therapeutic modalities early diagnosis and treatment is possible in many cases. Histopathology remains the gold standard in diagnosing Intracranial Posterior fossa tumours and necessary for the formulation of further management after neurosurgery.

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Section: Clinical Presentation Inmentioning

confidence: 99%

Clinicopathological spectrum of Intracranial Posterior Fossa Tumours and their Prognostic significance

Gubbala

Mattaparti

Bhavani³

2019

APALM

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Role of Magnetic Resonance Imaging in the Evaluation of Posterior Cranial Fossa Space-Occupying Lesions

SABINA SHAMS,

BASER SC,

RUMANA HITAWALA

2024

Asian J Pharm Clin Res

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Objectives: The current study was conducted with the objective to evaluate and characterize various posterior cranial fossa space-occupying lesions as solid, cystic, vascular, and infective. The current study aims to evaluate this and to help clinicians with early detection, exact site, and extent of the lesion. Methods: A Cross-sectional study was conducted over a period of 18 months (January 2021 to June 2022) in patients who were clinically suspected and who underwent magnetic resonance imaging to evaluate posterior fossa space-occupying lesions at Geetanjali Medical College and Hospital, Udaipur. Results: In our study, the most common posterior fossa space-occupying lesion was acoustic neuroma (12, 2l.82%) followed by arachnoid cyst (7, 12.73%). The most common space-occupying lesion in female patients was acoustic neuroma (7 patients, 30.43%) whereas in male patients, the most common space-occupying lesion was arachnoid cyst (6, 18.75%). There were almost equal numbers of intra (49.09%) and extra-axial cases (50.91%). Conclusion: Due to the restricted space, involvement of the crucial brain stem nuclei, and fourth ventricle, posterior fossa space-occupying lesions are regarded as critical brain lesions. Early diagnosis and treatment are now possible thanks to modern diagnostic and therapeutic modalities.

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Histopathologic Pattern of Posterior Cranial Fossa Tumours in a West African Tertiary Hospital

Salami¹,

Adeleye²,

Oyemolade³

et al. 2019

MJZ

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Introduction: The posterior cranial fossa contains many vital structures and mortality of patients with tumours occurring in this area is high. Studies done in other geographic locations showed a higher occurrence of posterior cranial fossa tumours in paediatric patients while benign tumours were more commonly seen. Epidemiological data of tumours in this area in our environment is scarce. This study was done to ascertain the histopathologic pattern of tumours in the posterior cranial fossa in a predominantly black population. Method: A ten-year retrospective study of histologically diagnosed posterior cranial fossa tumours seen in our hospital facility was done. A total of 72 cases in which neurosurgical intervention was carried out were identified and this included all age groups. The age, sex, site of tumour and histological diagnosis were extracted from the patients' records. Result: Adult patients predominated with 55.6% while the paediatric patients were 44.4%. The male to female ratio in the paediatric patients was 2.56:1 but the ratio was equal in the adult patients. WHO grade 1 tumours were the commonest tumours seen (45.8%) while grade II tumours were the least (4.2%). Medulloblastomas (20.83%), Pilocytic astrocytomas (18.6%) and Meningiomas (8.33%) were the commonest tumours seen. Commonest locations are in the cerebellar hemispheres (56.9%) and the fourth ventricle (13.89%). Conclusion: Our study showed a higher occurrence of Medulloblastomas in contrast to other studies which have shown more of Schwannomas, a tumour type that was rare in this study. The relatively low number of metastatic tumours in this study may be due to lack of presentation of such patients.

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Spectrum of Posterior Cranial Fossa Space Occupying Lesions- Our Experience at a Tertiary Care Centre

Cited by 3 publications

References 14 publications

Clinicopathological spectrum of Intracranial Posterior Fossa Tumours and their Prognostic significance

Clinicopathological spectrum of Intracranial Posterior Fossa Tumours and their Prognostic significance

Role of Magnetic Resonance Imaging in the Evaluation of Posterior Cranial Fossa Space-Occupying Lesions

Histopathologic Pattern of Posterior Cranial Fossa Tumours in a West African Tertiary Hospital

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