Spermatogenesis in goats with and without scrotum bipartition

Júnior, Antônio Augusto Nascimento Machado; Oliveira, Leonardo S.; Neto, Antônio Chaves de Assis; Alves, Flávio Ribeiro; Miglino, María Angélica; Carvalho, Maria Acelina Martins de

doi:10.1016/j.anireprosci.2011.12.012

Cited by 10 publications

(4 citation statements)

References 29 publications

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“…Several studies have reported stimulatory effects of Astragaloside (main compound extracted from AM ) [ 4 , 22 ] on cell proliferation, which was also observed in this study. Leydig cells influence sexual maturation of males by secreting testosterone, which is influenced by cell number and rate of steroidogenesis.…”

Section: Discussionsupporting

confidence: 85%

Effects of treatment with Astragalus Membranaceus on function of rat leydig cells

Jiang

Cao

Huang

et al. 2015

BMC Complement Altern Med

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BackgroundAstragalus membranaceus (AM) is a Chinese traditional herb which has been reported to have broad positive effects on many diseases, including hepatitis, heart disease, diabetes and skin disease. AM can promote cell proliferation, increase the activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx), and inhibit apoptosis by regulating the transcription of proto-oncogenes controlling cell death. While AM is included in some commercially available “testosterone boosting supplements”, studies directly testing ability of AM to modulate testosterone production are lacking. In the present study, we examined the effects of AM on Leydig cell function in vitro.MethodsRat Leydig cells were purified and treated with AM at different concentrations (0 μg/mL, 10 μg/mL, 20 μg/mL, 50 μg/mL, 100 μg/mL and 150 μg/mL) and cell counting-8 (CCK-8) assay, Enzyme-linked immunosorbent assay, quantitative real time PCR and analysis of activities of SOD and GPx were done respectively.ResultsTreatment with 100 μg/mL (P < 0.05) and 150 μg/mL AM (P < 0.01) significantly increased Leydig cell numbers. Treatment with AM (20 μg/mL, 50 μg/mL and 100 μg/mL) significantly increased testosterone production (P < 0.01). In addition, increased Leydig cell SOD and GPx activities were observed in response to 20 μg/mL and 50 μg/mL AM treatment (P < 0.01). Furthermore, expression of Bax mRNA was significantly decreased (P < 0.01), and the ratio of Bcl-2/Bax mRNA was significantly increased in response to 20 μg/mL AM in the culture medium (P < 0.05).ConclusionsResults supported a beneficial effect of AM on multiple aspects of rat Leydig cell function in vitro including testosterone production.

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Section: Discussionsupporting

confidence: 85%

Effects of treatment with Astragalus Membranaceus on function of rat leydig cells

Jiang

Cao

Huang

et al. 2015

BMC Complement Altern Med

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“…Meanwhile, the PRI (93.05 to 101.08) was lower than that of goats (102.08–105.80) from Ethiopia [ 14 ] but higher than that of goats (96.81–97.55) from Indonesia [ 17 ], considering that lower values correspond to meat biotype animals [ 23 ]. The PI, TPI, LPI, COI, RCTI, and LCI indices were similar to those obtained for goats from Indonesia [ 25 ] and higher than those for goats from Ethiopia [ 14 ]. Goats with higher values of PI, TPI, and LPI were oriented towards the meat biotype with good maternal and reproductive ability [ 9 , 16 ]; the same could be said for COI, which defines the goat of the Ayacucho region as dual purpose [ 30 ].…”

Section: Discussionsupporting

confidence: 72%

“…The genetic frequency for supernumerary teats is 0.34 [ 23 ], predisposing lactating goats to mastitis as this trait affects milking efficiency, causing teat lesions [ 24 ]. 32% of males exhibit scrotal bifurcation, which could be related to better spermatic parameters [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Phaneroptic characterization and zoometric indices of Creole goats in the Ayacucho Region, Peru: First step for breeding programs, selection, and conservation

Guerrera,

Estrada,

Padilla

et al. 2024

J Adv Vet Anim Res

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Objective: The purpose of this study is to evaluate the phenotypic characteristics and typification of Creole goats in five localities of the Ayacucho region in south-central Peru. Materials and Methods: Data from 149 goats (25 males and 124 females) were collected, excluding animals under 2 years of age, pregnant, and sick. Seven qualitative characteristics and 11 zometric measurements were evaluated, and then 9 zometric indices were estimated. Results: In the region, goats with composite colors predominated (76.50%). Additionally, supernumerary (24.20%) and divergent teats (22.60%) were observed in females, while males exhibited a scrotal bifurcation (32.00%). The origin of the flock had a significant effect (p < 0.05) on body measurements, as well as on pelvic index, transverse pelvic index, longitudinal pelvic index, compactness index, and load cannon bone index, except for body index (BOI), proportionality index, dactyl thorax index (DTI), and relative cannon bone thickness index (p > 0.05). In the Ayacucho region, there is a predominance of light animals (57.72%) with a significant DTI (p < 0.05) among the populations, including goats with good balance and capable of walking long distances. Furthermore, there are compact animals (47.65%) with a significant BOI (p < 0.05) among the flock populations, which animals are of the biotype of meat. Conversely, the strongest positive correlation (r = 0.89) was discovered between chest girth and body weight. Conclusion: In the Ayacucho region, there are various creole goat biotypes range from light to very compact heavy goats, with a predominance of meat biotype animals, as well as a marked size dimorphism between localities of origin.

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“…The tubular morphology method has been applied to many species, and eight stages of seminiferous tubules have been identified in the studies carried out in testis of goats (Capra hircus) [ 24 , 25 ], donkeys (Equus asinus) and mules (Equus mulus) [ 26 ], landrace boars (Sus scrofa domesticus) [ 27 ], crioulo horses (Equus ferus caballus) [ 28 ], dogs ( Canis familiaris) [ 29 ], and Javan muntjacs [ 18 ], whereas the second method has been applied to the testicular tissue of gerbils (Meriones unguiculatus) [ 30 ], long-tailed macaques [ 19 ], indigenous bull (Bos indicus) [ 31 ], mice (Mus musculus) [ 32 ], micromini pigs (Sus scrofa domesticus) [ 33 ], and rams [ 20 ]. However, the data regarding the stages of the seminiferous epithelium and spermatid development during spermatogenesis in the testis of Aceh bull have not been reported yet.…”

Section: Introductionmentioning

confidence: 99%

Identification and Determination of the Seminiferous Epithelium Stages and Spermatid Development in the Testis of Aceh Bull (Bos indicus)

Wahyuni,

Siregar,

Gholib

et al. 2023

Veterinary Medicine International

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This study was conducted to describe the stages of seminiferous epithelium (SE), determine the relative frequency of the stages, and identify the steps of spermatid development during spermatogenesis in the testicular tissue of Aceh bull. Seven pairs of the testicular organs of Aceh bull (Bos indicus) were used and then processed in a histological manner for staining using haematoxylin and eosin (H&E) and periodic acid-Schiff-haematoxylin (PAS-H). The stages of seminiferous tubules were examined using a tubular morphology method while spermatid development was observed based on the acrosome formation during spermatid development. Eight stages (stages I to VIII) of SE were found in the testicular seminiferous tubules of Aceh bull. Furthermore, the percentage of the relative frequency of each stage was 25.48, 15.38, 12.92, 4.74, 14.97, 10.69, 10.74, and 5.08%, respectively, with the relative frequency of premeiotic, meiotic, and postmeiotic phases being 53.78, 4.74, and 41.48%, respectively. Spermatid development from round to elongated spermatids occurred in 14 steps. Steps 1 to 7 were observed in stage I, steps 8 and 9 in stage II, steps 10 and 11 in stage III, step 12 in stage IV, step 13 in stages V and VI, and step 14 in stages VII and VIII. These findings can be used as a basis for further studies, particularly in evaluating the abnormality of the cellular composition of the seminiferous tubule in each stage of spermatogenesis and also in determining daily sperm production in Aceh bull.

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Spermatogenesis in goats with and without scrotum bipartition

Cited by 10 publications

References 29 publications

Effects of treatment with Astragalus Membranaceus on function of rat leydig cells

Effects of treatment with Astragalus Membranaceus on function of rat leydig cells

Phaneroptic characterization and zoometric indices of Creole goats in the Ayacucho Region, Peru: First step for breeding programs, selection, and conservation

Identification and Determination of the Seminiferous Epithelium Stages and Spermatid Development in the Testis of Aceh Bull (Bos indicus)

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