Spick-and-span protocol for designing of silica-supported enantioselective organocatalyst for the asymmetric aldol reaction

Asymmetric hydrogenation using a covalently immobilized Ru-BINOL-AP@MSNs catalyst

“…S6B, ESI †). 32 The TGA curves of neat MSNs, AP@MSNs, BINOL-AP@ MSNs, and Ru-BINOL-AP@MSNs are shown in Fig S7 (ESI †). According to Fig.…”

“…Using a reported post-synthetic grafting technique, 32 an amine-functionalized MSNs were synthesized. Here in this method, 1.0 g of pre-dried calcinated MSNs was mixed with dry toluene (10 mL) in a 100 mL round-bottom flask.…”

DFT stimulation and experimental insights of chiral Cu(ii)–salen scaffold within the pocket of MWW-zeolite and its catalytic study

“…In summary, these complexes have demonstrated high reusability and stability in zeolite-Y, making them attractive for industrial applications. In light of our previous efforts, [35][36][37][38] herein we report for the first time the encapsulation of chiral Cu(II)-salen complexes inside MWW-framework zeolite pores and tested for one-pot multicomponent Biginelli reaction in liquid phase. To comprehend the nature of the structural and electronic changes that occur in complexes under the influence of the MWW zeolite framework, a density functional theory (DFT) approach has been applied.…”

Organocatalytic chiral polymeric nanoparticles for asymmetric aldol reaction

“…44 Chetan K. Modi and his lab-workers have explored a new inexpensive strategy to synthesize l -proline derivatives onto the silica matrix without the protecting/deprotecting steps which give 99% enantioselectivity in the application of asymmetric aldol reaction. 45 Another research was published where the catalyst was prepared in situ by combining the tridentate ligand derived from 1,1′-Bi-2-naphthol, (BINOL), Ti(OiPr) 4 and salicylic acid in the presence of trimethylsilyl chloride and triethyl amine. 46 Tang and co-workers 47 synthesized a pyrrolidine derivative with a terminal hydroxyl group, which efficiently catalyses the direct aldol reactions of aromatic and aliphatic aldehydes in neat acetone with high enantioselectivity, >99% ee.…”