Spindle cell carcinoma of the nasopharynx

Abstract

A case of spindle cell carcinoma of the nasopharynx is reported and its current management is reviewed. Surgical excision of the nasopharyngeal tumour may be the treatment of choice in some cases.

An unusual case of nasopharyngeal carcinoma

“…The first case of spindle cell type NPC was described by Nofal from Bristol, United Kingdom in 1983 2,3 . In a series in 1983 reported 140 cases of NPC.…”

“…But in Eastern and Southeast Asia it comprises 18% of all malignant tumours 1 . However, spindle cell type of NPC is extremely rare all over the world and described in very few papers 2,3 . Usual manifestations of NPC include neck lump due to metastasis to cervical lymph nodes, ear fullness, hearing loss due to blockage of Eustachian tubes along with nasal bleeding and obstruction 1,4,5 .…”

Myoepithelial carcinoma of the nasopharynx: Case report of a rare entity

“…[5] Nilles and associates[6] and Tuncel and colleagues[7] reported only two cases of malignant myoepithelioma in the rhinopharynx that were confirmed histologically and immunohistochemically. In 1983, Nofal[8] described a poorly differentiated spindle-cell carcinoma that could have been the third case of rhinopharyngeal myoepithelial carcinoma.…”

“…[11] Several surgical approaches have been proposed, depending on the size and site of the tumor. [6–812] We adopted excision of the tumor with paramedian mandibulotomy in conjunction with a transpalatal approach. To our knowledge, this patient is the only case of nasopharyngeal MC treated with this technique.…”

Malignant Myoepithelioma of the Rhinopharynx: Case Report

“…9 Nilles and associates 11 and Tuncel and colleagues 12 reported the only two cases of MM in the rhinopharynx that have been confirmed histologically and immunohistochemically. In 1983, Nofal 13 described a poorly specified spindle-cell carcinoma that could have been the third case of rhinopharyngeal MM (see Table 1).…”