Spindle cell carcinoma of the palatine tonsil: report of a diagnostic pitfall and literature review

Minami, Shujiro; Shinden, Seiichi; Yamashita, Taku

doi:10.1016/j.amjoto.2007.02.006

Cited by 25 publications

(28 citation statements)

References 9 publications

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“…For tumors of the oral cavity as well as the larynx, surgery is the mainstay of treatment. In comparison to radiation therapy alone, the prognosis is better for surgery [13] [14]. Chemotherapy has proven to have good results as part of neo-adjuvant and adjuvant treatment in helping to reduce the tumor size.…”

Section: Discussionmentioning

confidence: 99%

“…However, when used as a sole treatment modality, it has ambiguous results [15]. Treatment also depends on various other factors; like low grade tumor, small tumor size, absence of previous radiation therapy and polypoidal growth indicate good prognosis [14], while factors that influence choice of treatment clearly depends primarily upon the extent of lesion and surgeon being able to excise the lesion completely. This is followed by Radiation and +/− chemotherapy [15].…”

Section: Discussionmentioning

confidence: 99%

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Spindle Cell Carcinoma of the Maxilla: A Case Report of Rare Entity

Junaid¹,

Kazi²,

Qadeer³

2017

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Spindle cell carcinoma also known as sarcomatoid carcinoma is a rare highly aggressive tumor which is histologically different from squamous cell ca and mesenchymal cancers. Only hands full of cases have been reported in literature since 1957 and hence no proper treatment protocol has been devised yet. We present such a case of thirty-four-year-old female who presented with spindle cell carcinoma of the maxilla at our department and was treated with extensive surgery followed by chemotherapy and radiation therapy. Spindle cell carcinoma is generally associated with poor prognosis and hence literature supports use of post operative Chemo and Radiotherapy for better result and decrease chance of local recurrence.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Spindle Cell Carcinoma of the Maxilla: A Case Report of Rare Entity

Junaid¹,

Kazi²,

Qadeer³

2017

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“…Growth configuration is often exophytic polypoid, but sessile, nodular or endophytic configuration has also been described. The lesion usually has an extensive surface ulceration with friable, fibrinoid necrosis of variable thickness or shaggy exudates 5,8 . Radiation, trauma, tobacco use or alcohol consumption seemed to play a role in etiological factors 8 .…”

Section: ⅲ Discussionmentioning

confidence: 99%

“…Furthermore, adjuvant irradiation might be of benefit in cases in which the surgical margins are positive or in patients with nodal metastasis at the time of diagnosis 2 . Prognosis is related to location, tumor size, depth of invasion, stage of disease and with the presence of any keratin staining in the spindle cells 8 . A tumor of the oral cavity and oropharynx is potentially aggressive and seems recur easily and to metastasize easily 9 .…”

Section: ⅲ Discussionmentioning

confidence: 99%

Sarcomatoid carcinoma of the mandible: report of a case

Kwon

Choi

Song

et al. 2010

J Korean Assoc Oral Maxillofac Surg

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Sarcomatoid carcinoma is a rare and occurs mainly in the upper aerodigestive tract such as the oral cavity, esophagus and vocal cords. It is a unique variant of squamous cell carcinoma. We report the case of a patient with spindle cell squamous cell carcinoma involving the mandible. At initial examination, overlying mucosa of that lesion was normal appearance. One week later, that lesion showed ulcerative and bloody change and rapid growth in size. This case showed unpredictable rapid growth although rapid growth in size was suspected of undergoing malignancy.Key words: Sarcomatoid carcinoma, Mandible, Mandibular neoplasms [원고접수일 2010.3.15 / 1차수정일 2010.4.15 / 2차수정일 2010.4.29 / 게재확정일 2010.5.13] Abstract (J Korean Assoc Oral Maxillofac Surg 2010;36:228-30)

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“…5,6 In addition, in several cancers, NSCs have been reported to associate with poor prognosis in several cancers. 5,7 Clarifying the biological characteristics and mechanisms of NSCs may greatly impact the treatment of PC, a disease in which metastasis and recurrence can easily occur, even in a relatively early stage. The emergence of NSCs in various cancers has been associated with epithelial-mesenchymal transition (EMT).…”

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confidence: 99%