Spindle cell/pleomorphic lipoma of the cheek: A case report

Yoshida, Yu; Tamura, Takayuki; Takubo, Kazuko; Otsuki, Kazuma; Doi, Rieko; Kodani, Isamu

doi:10.1002/osi2.1010

Cited by 4 publications

(4 citation statements)

References 19 publications

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“…3 ASCLT has similar histopathological features to spindle-shaped lipoma, and immunohistochemical staining is effective in obtaining a definite diagnosis. 4 In ASCLT, the presence of CD34 is often observed in tissue samples, which is helpful for diagnosis. [1][2][3]5 Mariño et al have reported that the diagnostic sensitivity of CD34 for ASCLT is 64% and that MDM2 is not observed in tissue samples in ASCLT.…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Atypical Spindle Cell Lipomatous Tumor of the Tongue

et al. 2020

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Herein, we report a case of atypical spindle cell lipomatous tumor (ASCLT) on both sides of the tongue in a 74-year-old male patient. The patient was referred to our department for treatment of the masses in the tongue. Several elastic soft indolent masses were detected during the first examination. The masses were well defined, and their consistency was similar to that of adipose tissues. No signs of induration were observed in the surrounding tissues. The patient was not aware of the masses, which were only detected during his visit at the dental clinic that referred him to our institution. Thus, the onset of the masses remains unknown. ASCLT was identified via histopathological examination. Then, tumor excision was performed under general anesthesia. Thirteen months after surgery, the condition of the patient was good, and signs of local recurrence or postoperative metastasis were not observed.

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Section: Discussionmentioning

confidence: 99%

A Case Report of Atypical Spindle Cell Lipomatous Tumor of the Tongue

et al. 2020

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“…Lipomas are termed giant when they are larger than 5 cm, and 75% of cases are symptomatic [9]. Pleomorphic lipoma accounts for 1.5% of all lipomas [10]. In our case, the diameter of the pleomorphic lipoma was more than 10 cm.…”

Section: Discussionmentioning

confidence: 60%

“…Pleomorphic lipoma is very di cult to diagnose, and is not easy to distinguish from highly specialized liposarcoma [10]. The diagnosis of pleomorphic lipoma is mainly based on CT, magnetic resonance imaging (MRI), and histopathology.…”

Section: Discussionmentioning

confidence: 99%

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Giant Pleomorphic Lipoma With Malignant Transformation in the Buttock: a Rare Case Report and Literature Review

Feng¹,

Xu²,

Xu³

et al. 2021

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Background: Pleomorphic lipoma is a benign tumor, which is often located in the neck, shoulder, and other subcutaneous tissues. Pleomorphic lipoma with malignant transformation in the buttock is rarely reported.Case Presentation: A 53-year-old male attended to our department with a large mass in his buttock that had been present for about one year, leading to difficulty with walking and defecation. Computed tomography (CT) showed a 10. 2 × 8. 3 cm mass with lumpy and mixed low to medium density shadows in the right side of the lower part of the tailbone. Color Doppler ultrasound showed that the skin and subcutaneous tissues of the right buttock were thickened with lymphedema. Pre-operative pathology revealed a large amount of adipose and fusiform fibrous tissues with obvious blood vessels. The patient underwent complete resection of the mass in the right buttock. Postoperative pathology indicated that the tumor was pleomorphic lipoma with malignant transformation. The patient recovered well and was discharged from the hospital at day 12 post-surgery. Follow up at 6 months did not find any symptoms of tumor recurrence.Conclusions: Pleomorphic lipoma with malignant transformation is rare. CT, magnetic resonance imaging (MRI) and histopathology are the main methods used to diagnose pleomorphic lipoma. Complete resection of the tumor is vital to treat giant pleomorphic lipoma successfully.

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Pleomorphic lipoma of the loin region; a case report with literature review

Mirawdali

Salih

Salih³

et al. 2022

International Journal of Surgery Open

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Introduction: Pleomorphic lipoma (PL) is a rare type of lipoma that accounts for only 1.5% of all adipocytic tumors. The aim of this report is to present the first case of PL in the flank. Case report: A 67-year-old male presented with fullness of the right flank, without any other symptoms. On examination there was a soft mass that mimicked hernia. Laboratory findings showed elevated renal function tests (blood urea of 46.1 mg/dl and s. creatinine of 1.59 mg/dl) Computed tomography (CT) scan showed a large fatty mass lesion (25 × 18 cm) in the right lower abdomen under the right-side external oblique muscle and over the internal oblique muscle with no extension to the abdomen, imaging features were suggestive of lipoma. The patient was operated for transverse flank incision to completely remove the mass, which was yellow in color. Histopathology confirmed the diagnosis PL. The operation was uneventful. Discussion: PL is characterized by the admixture of variable sized adipocytes and pleomorphic multinucleated giant cells with floret-like arrangement. It is a disease of old ages with higher male predominance, and mostly occurs in the subcutaneous tissue of the posterior neck, upper back and shoulders. PL localization in deep tissues is highly rare with a very few cases being reported in the intramuscular region. Conclusion: PL in the flank is an exceptional finding with the current case being the first report in the literature. Histopathology is the only key to provide definitive diagnosis. Highlights

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Spindle cell/pleomorphic lipoma of the cheek: A case report

Cited by 4 publications

References 19 publications

A Case Report of Atypical Spindle Cell Lipomatous Tumor of the Tongue

A Case Report of Atypical Spindle Cell Lipomatous Tumor of the Tongue

Giant Pleomorphic Lipoma With Malignant Transformation in the Buttock: a Rare Case Report and Literature Review

Pleomorphic lipoma of the loin region; a case report with literature review

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