2019
DOI: 10.1080/15513815.2019.1600625
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Spindle Epithelial Tumor with Thymus-Like Differentiation (SETTLE): A Case Report

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Cited by 7 publications
(13 citation statements)
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“…1,8 Accurate diagnosis of SETTLE can be challenging due to its rarity and resemblance to other spindle cell predominant tumors. 5 Histologically, SETTLE is a cellular tumor, with fibrous septae separating the tumor into lobules/nodules with variable architectural appearances. The architecture may show a mixture of reticulated, microcystic, and/or hyalinized fascicles of spindle cells merging with areas showing an epithelial appearance, including glomeruloid, tubulo-papillary, glandular, and cystic.…”
Section: Case Reportmentioning
confidence: 99%
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“…1,8 Accurate diagnosis of SETTLE can be challenging due to its rarity and resemblance to other spindle cell predominant tumors. 5 Histologically, SETTLE is a cellular tumor, with fibrous septae separating the tumor into lobules/nodules with variable architectural appearances. The architecture may show a mixture of reticulated, microcystic, and/or hyalinized fascicles of spindle cells merging with areas showing an epithelial appearance, including glomeruloid, tubulo-papillary, glandular, and cystic.…”
Section: Case Reportmentioning
confidence: 99%
“…First, SETTLE is rare and fine-needle aspirate cytology alone lacks sensitivity for a definitive diagnosis due to its similarity with other thyroid and non-thyroid neoplasms. 5 In a 28-year-old man with a history of a hemithyroidectomy and a mass consistent with SETTLE, a neck nodule 5 years postsurgery would most likely represent a recurrence. However, other neck lesions would need to be excluded.…”
Section: Case Reportmentioning
confidence: 99%
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