2014
DOI: 10.1007/s00586-014-3191-4
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Spine MR imaging features of subacute combined degeneration patients

Abstract: Symmetric T2-hyperintensity within dorsal column of spinal cord is commonly seen in SCD patients with a linear pattern in the cervical spine and a nodular pattern in the thoracic spine.

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Cited by 37 publications
(16 citation statements)
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“…On the axial planes, the bilateral high-intensity T2 signals within the posterior funiculus of the cervical spinal cord resemble the appearance of an inverted letter “V,” thus called the inverted V-sign [10 , [12] , [13] , [14] . One case series mentioned high-intensity T2 signal resembling a “dumbbell” or “binoculars” on the axial planes of the thoracic spinal cord [15] . Contrast enhancement of the spinal cord has been sporadically described [10 , 16] .…”
Section: Discussionmentioning
confidence: 99%
“…On the axial planes, the bilateral high-intensity T2 signals within the posterior funiculus of the cervical spinal cord resemble the appearance of an inverted letter “V,” thus called the inverted V-sign [10 , [12] , [13] , [14] . One case series mentioned high-intensity T2 signal resembling a “dumbbell” or “binoculars” on the axial planes of the thoracic spinal cord [15] . Contrast enhancement of the spinal cord has been sporadically described [10 , 16] .…”
Section: Discussionmentioning
confidence: 99%
“…En un artículo publicado recientemente por Sun y cols. [16] se evaluaron 8 pacientes con degeneración subaguda combinada. De ellos, 7 presentaron hiperintensidad del aspecto posterior del cordón espinal; 5 lo presentaron en la médula cervical, y 2, en la médula torácica.…”
Section: Discussionunclassified
“…Two studies have shown that elevated levels of Hcy and MMA were detectable in 15% to 33% of patients with normal Schilling tests, indicating the increased specificity of laboratory measurements in diagnosing B 12 deficiency. 29,30 Magnetic resonance imaging (MRI) is not normally indicated for patients with B 12 deficiency, but some reports have noted characteristic V-shaped hyperintensity on T2-imaging when present in the cervical cord and "bumbell" or bilateral nodular shape when present in the thoracic cord in patients with severe myelopathy 31,32 (Figure 2).…”
Section: Vitamin B 12 : Mechanism Of Actionmentioning
confidence: 99%