Spiropyran‐Conjugated Pluronic as a Dual Responsive Colorimetric Detector

Oh, Yeon Jeong; Nam, Jeong A.; Al-Nahain, Abdullah; Lee, Sangkug; In, Insik

doi:10.1002/marc.201200416

Cited by 28 publications

(16 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Photochromic spiropyran (SP) was conjugated with the PPNM polymer to prepare a PEG‐g‐[poly(NIPAAm‐co‐MAA‐SP)] polymer (SP‐PPNM; Figure S1 in the Supporting Information) 27. 28 In detail, spiropyran (0.07 g) was mixed with PEG‐grafted poly(NIPAAm‐co‐MAA) (1 g) by treatment with equimolar (equiv.) DMAP (0.0277 g) and DCC (0.0468 g) in dry DCM (30 mL).…”

Section: Methodsmentioning

confidence: 99%

Photo‐ and pH‐Tunable Multicolor Fluorescent Nanoparticle‐Based Spiropyran‐ and BODIPY‐Conjugated Polymer with Graphene Oxide

Sharker

Jeong

Kim

et al. 2014

Chemistry An Asian Journal

Self Cite

View full text Add to dashboard Cite

We report a stimuli-responsive fluorescent nanomaterial, based on graphene oxide coupled with a polymer conjugated with photochromic spiropyran (SP) dye and hydrophobic boron dipyrromethane (BODIPY) dye, for application in triggered target multicolor bioimaging. Graphene oxide (GO) was reduced by catechol-conjugated polymers under mildly alkaline conditions, which enabled to formation of functionalized multicolor graphene nanoparticles that can be induced by irradiation with UV light and by changing the pH from acidic to neutral. Investigation of these nanoparticles by using AFM, fluorescence emission, and in vitro cell and in vivo imaging revealed that they show different tunable colors in bioimaging applications and, more specifically, in cancer-cell detection. The stability, biocompatibility, and quenching efficacy of this nanocomposite open a different perspective for cell imaging in different independent colors, sequentially and simultaneously.

show abstract

Section: Methodsmentioning

confidence: 99%

Photo‐ and pH‐Tunable Multicolor Fluorescent Nanoparticle‐Based Spiropyran‐ and BODIPY‐Conjugated Polymer with Graphene Oxide

Sharker

Jeong

Kim

et al. 2014

Chemistry An Asian Journal

Self Cite

View full text Add to dashboard Cite

show abstract

“…1) [19]. Inspired by such switchable characteristic with different remarkable properties, e.g., absorption spectra, dipole moment, dielectric constant, geometrical structure, and coordination property etc., light sensitive polymers containing spiropyran units have been fabricated for specific applications such as bioimaging [20], controlled release [1,21,22], mechanic sensor [23], colorimetric detector [24,25], etc. On the other hand, acid/base-responsive polymers in aqueous media have drawn increasing attention [26][27][28].…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Water-Soluble Spiropyran-Modified Poly(acrylic acid) Micelles and Their Optical Behaviors

Xue

Zhang

Tian

2018

J. Photopol. Sci. Technol.

View full text Add to dashboard Cite

In this study, a spiropyran derivative (SPOH) is firstly grafted onto a polymer backbone of a poly(acrylic acid) (PAA) via an esterification process. The synthesized spiropyran-modified poly(acrylic acid) (PAA-SP) polymer is characterized by FTIR and 1 H NMR. The synthesized PAA-SP is then dissolved into water to achieve water-soluble micelles. The optical behaviors of PAA-SP micelles are investigated by ultraviolet-visible (UV-Vis) absorption spectra and fluorescence emission spectra under acid/base and light stimuli in aqueous solution. Our experimental results reveal that the as-prepared PAA-SP micelles are water-soluble and show good photochromic and emissive behaviors. Meanwhile, the optical behaviors of the micelles are light-responsive and acid/base-responsive and hence can be tailored via the adjustments of both light and pH value of the solution sample. And our results may be meaningful for practical application of hydrophobic spiropyran derivatives in aquatic environments.

show abstract

“…(a)) and the fluorescence spectra (Fig. (b)) . A 0.25 mg/mL aqueous solution of the SP‐PS beads was irradiated in cycles with UV light (4 min) followed by visible light (4 min), and the UV–Vis absorption spectra were measured.…”

Section: Resultsmentioning

confidence: 99%

“…CCDP‐q‐[PEG‐g‐poly(DMA‐co‐MAA)] (C‐PDM, Mn:13,200) was synthesized, following a method similar to our previous work . To prepare the spiropyran conjugated CCDP‐q‐[PEG‐g‐poly(DMA‐co‐MAA)] (C‐PDM), 0.177 g of spiropyran was mixed with 3 g of C‐PDM by reaction with equimolar equivalents of DMAP (0.071 g) and DCC (0.12 g) in dry dichloromethane (70 mL).…”

Section: Methodsmentioning

confidence: 99%

“…Spiropyran can exist in two different forms, namely the ring‐closed colorless spiropyran (SP) and the ring‐open colored merocyanine (MC) form. These two forms are interchangeable, with the SP form converting to the MC form upon UV light irradiation, and the reverse reaction taking place upon irradiation with visible light . The colorless SP form converts easily into the polyhydrophilic colored MC form under UV light irradiation through homolytic cleavage of the C‐O bond from cyclic form (spiro carbon to furan oxygen) in a ring‐opening reaction …”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Photo‐switchable spiropyran immobilized polystyrene beads using catechol chemistry

Kang

Cho

Islamy

et al. 2017

Surface & Interface Analysis

Self Cite

View full text Add to dashboard Cite

Catechol and spiropyran functional groups were conjugated to a polymer backbone, allowing immobilization on polystyrene beads (PS beads). The final product was capable of stably reproducing the optical properties of spiropyran. Through the outstanding surface adhesion properties of the catechol functional group, spiropyran was immobilized on PS beads. Switchable photoluminescence in the spiropyran coated PS bead surfaces was observed depending on irradiation with either UV or visible light. The surfaces of the PS beads were morphologically examined by field emission scanning electron microscopy and X-ray photoelectron spectroscopy was used for characterization of the constituent atoms. Furthermore, UV-Vis and fluorescence spectroscopy were used to confirm conversion between the spiropyran (SP) and merocyanine (MC) forms through UV or visible light irradiation on SP, while fluorescent images for both SP and MC were studied using confocal laser scanning microscopy. The confocal images of the SP-PS beads system onto MDAMB-231 cells under UV and visible light indicate the cellular uptake by emerging color within the cytoplasm. Advancing study, the remaining catechol groups can confers adhesive properties, given by contact angle data of various coated surfaces film. These stimuli-responsive coatings are compatible as drawing switchable photochromic material on versatile substrate shown in confocal images of propylene film. Overall, this great water solubility and biocompatibility PS beads system also showed potential as cell bio-imaging light stimuli responsive material, and the benefits of this system can also possibly address coat able advanced material for a wide range of surface light sensor applications.

show abstract

Spiropyran‐Conjugated Pluronic as a Dual Responsive Colorimetric Detector

Cited by 28 publications

References 29 publications

Photo‐ and pH‐Tunable Multicolor Fluorescent Nanoparticle‐Based Spiropyran‐ and BODIPY‐Conjugated Polymer with Graphene Oxide

Photo‐ and pH‐Tunable Multicolor Fluorescent Nanoparticle‐Based Spiropyran‐ and BODIPY‐Conjugated Polymer with Graphene Oxide

Synthesis of Water-Soluble Spiropyran-Modified Poly(acrylic acid) Micelles and Their Optical Behaviors

Photo‐switchable spiropyran immobilized polystyrene beads using catechol chemistry

Contact Info

Product

Resources

About