Sponging up metals: Bacteria associated with the marine sponge Spongia officinalis

Bauvais, Cléa; Zirah, Séverine; Piette, Laurie; Chaspoul, Florence; Domart‐Coulon, Isabelle; Chapon, Virginie; Gallice, Philippe; Rebuffat, Sylvie; Pérez, Thierry; Bourguet‐Kondracki, Marie‐Lise

doi:10.1016/j.marenvres.2014.12.005

Cited by 53 publications

(32 citation statements)

References 54 publications

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“…In this study, the particular metabolomic profile observed for the samples collected at Cortiou in 2013 was partly explained by the presence of the marine pollutant coconut C 11 diethanolamide. It coincided with a high copper content measured in sponge and seawater samples [13]. The detection of these two pollutants within the sponge at this time point suggests a local anthropogenic pressure, which can be sensed within S. officinalis .…”

Section: Resultssupporting

confidence: 72%

“…For example, furospongin-1 displays antibacterial, antiprotozoal and cytotoxic activities [9,10,11], while furospongin-2 and furospongin-5 exhibit cytotoxic activities [12]. S. officinalis has also been shown to harbor a dense and diverse bacterial community [13,14] and to accumulate high concentrations of heavy metals [13,15]. Given the influence of environmental conditions on both bacterial and metal contents within the sponge, S. officinalis has been previously proposed as a bioindicator of water quality [14,16].…”

Section: Introductionmentioning

confidence: 99%

“…Our objectives were: (i) to evaluate the influence of site and time on collection on the metabolomic profile within the sponge and presence of potential biomarkers of anthropogenic pollution; and (ii) to assess the potential of metabolomics for the discovery of new natural compounds, even in an extensively explored species. Untargeted LC–MS metabolomic profiling was performed on extracts from sponge samples collected at two sites located near Marseille (South of France), which were differentially impacted by urban sewage in terms of bacterial diversity and metal content as previously reported [13]. In addition, LC–MS/MS analyses and molecular networking were used to search for new compounds related to the metabolomic clustering.…”

Section: Introductionmentioning

confidence: 99%

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Furanoterpene Diversity and Variability in the Marine Sponge Spongia officinalis, from Untargeted LC–MS/MS Metabolomic Profiling to Furanolactam Derivatives

et al. 2017

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The Mediterranean marine sponge Spongia officinalis has been reported as a rich source of secondary metabolites and also as a bioindicator of water quality given its capacity to concentrate trace metals. In this study, we evaluated the chemical diversity within 30 S. officinalis samples collected over three years at two sites differentially impacted by anthropogenic pollutants located near Marseille (South of France). Untargeted liquid chromatography—mass spectrometry (LC–MS) metabolomic profiling (C18 LC, ESI-Q-TOF MS) combined with XCMS Online data processing and multivariate statistical analysis revealed 297 peaks assigned to at least 86 compounds. The spatio-temporal metabolite variability was mainly attributed to variations in relative content of furanoterpene derivatives. This family was further characterized through LC–MS/MS analyses in positive and negative ion modes combined with molecular networking, together with a comprehensive NMR study of isolated representatives such as demethylfurospongin-4 and furospongin-1. The MS/MS and NMR spectroscopic data led to the identification of a new furanosesterterpene, furofficin (2), as well as two derivatives with a glycinyl lactam moiety, spongialactam A (12a) and B (12b). This study illustrates the potential of untargeted LC–MS metabolomics and molecular networking to discover new natural compounds even in an extensively studied organism such as S. officinalis. It also highlights the effect of anthropogenic pollution on the chemical profiles within the sponge.

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Section: Resultssupporting

confidence: 72%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Furanoterpene Diversity and Variability in the Marine Sponge Spongia officinalis, from Untargeted LC–MS/MS Metabolomic Profiling to Furanolactam Derivatives

et al. 2017

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“…Isodictya compressa was first described by Esper in 1794, while Waltherarndtia caliculatum was described by Kirkpatrick in 1903, both of which are endemic to South Africa [30,31,32,33] and the bacteria associated with these three marine sponges have not been investigated. Axinella and Spongia species have a global distribution and the microbial populations of some species of these sponge genera have been studied [34,35,36,37]. We first determined the bacterial diversity associated with these five sponges, then isolated bacteria from two of these and demonstrated their ability to produce antibacterial compounds.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activities of Bacteria Isolated from the Marine Sponges Isodictya compressa and Higginsia bidentifera Collected from Algoa Bay, South Africa

et al. 2017

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Due to the rise in multi-drug resistant pathogens and other diseases, there is renewed interest in marine sponge endosymbionts as a rich source of natural products (NPs). The South African marine environment is rich in marine biota that remains largely unexplored and may represent an important source for the discovery of novel NPs. We first investigated the bacterial diversity associated with five South African marine sponges, whose microbial populations had not previously been investigated, and select the two sponges (Isodictya compressa and Higginsia bidentifera) with highest species richness to culture bacteria. By employing 33 different growth conditions 415 sponge-associated bacterial isolates were cultured and screened for antibacterial activity. Thirty-five isolates showed antibacterial activity, twelve of which exhibited activity against the multi-drug resistant Escherichia coli 1699, implying that some of the bioactive compounds could be novel. Genome sequencing of two of these isolates confirmed that they harbour uncharacterized biosynthetic pathways that may encode novel chemical structures.

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“…Heavy metals are produced from a variety of natural and anthropogenic sources [1] . In aquatic environments, heavy metal pollution results from direct atmospheric deposition, geologic weathering or through the discharge of agricultural, municipal, residential or industrial waste products, also via wastewater treatment plants [2][3][4] .…”

Section: Introductionmentioning

confidence: 99%

Biochemical Markers of Oxidative Stress in Brain of Zebrafish Danio rerio Exposed to Different Heavy Metals Lead and Cobalt

Singh¹,

Ansari²

2017

IJLSSR

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ABSTRACT-Aquatic organisms have been considered to concentrate metals several times greater than environmental levels. Fishes have been used for many decades to evaluate the pollution status of water and thus considered as excellent biological indicator of heavy metals in aquatic environments. Heavy metals are natural tress components of the aquatic environment, but their levels have increased due to domestic, industrial, mining and agricultural activities. These heavy metals when accumulated in the fish tissues, they damage and weaken the mechanisms concerned leading to physiological, pathological and biochemical changes. The lead is non essential element while cobalt is an essential element for living organisms but its presence in fresh water in higher concentration are toxic to organism's brain, liver, ovary, kidney and gills of the fish. The present study was aimed to investigate the changes due to two heavy metals (lead & cobalt) on the activity of the antioxidant enzyme, Catalase (CAT), Reduced glutathione (GSH), and Lipid peroxidation (LPO) in the brain of Danio rerio during 5, 10, 15 and 20 days of exposure period. For this study adult fishes were exposed to four different concentrations viz., 20, 30, 40 and 50 mg/l of cobalt and 5, 9, 13, and 17 mg/l of lead.

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Sponging up metals: Bacteria associated with the marine sponge Spongia officinalis

Cited by 53 publications

References 54 publications

Furanoterpene Diversity and Variability in the Marine Sponge Spongia officinalis, from Untargeted LC–MS/MS Metabolomic Profiling to Furanolactam Derivatives

Furanoterpene Diversity and Variability in the Marine Sponge Spongia officinalis, from Untargeted LC–MS/MS Metabolomic Profiling to Furanolactam Derivatives

Antibacterial Activities of Bacteria Isolated from the Marine Sponges Isodictya compressa and Higginsia bidentifera Collected from Algoa Bay, South Africa

Biochemical Markers of Oxidative Stress in Brain of Zebrafish Danio rerio Exposed to Different Heavy Metals Lead and Cobalt

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