Spontaneous and Induced Water Intoxication in Two Cases of Hypopituitarism

Wynn, V.; Garrod, Oliver

doi:10.1136/bmj.1.4912.505

Cited by 15 publications

(3 citation statements)

References 11 publications

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“…Another, the water load test, can also be dangerous since these patients are unable to excrete more than 10-15 Y of water load. The administration of a litre or so of water in the performance of this test may lead to water intoxication (Wynn & Garrod 1955). The water load test is non-specific.…”

mentioning

confidence: 99%

The Endocrinology of Pituitary Tumours

Ross¹

1961

Proceedings of the Royal Society of Medicine

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mentioning

confidence: 99%

The Endocrinology of Pituitary Tumours

Ross¹

1961

Proceedings of the Royal Society of Medicine

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“…The difficulty in treating these cases is not that of diagnosing pituitary insufficiency, but rather in deciding what acute biochemical changes have occurred in patients who have been living in a state of endocrine deficiency for many years (Whittaker and Whitebead, 1954;Wynn and Garrod, 1955).…”

Section: Commentmentioning

confidence: 99%

“…No gross and specific physical signs betray water retention-pitting oedema is absent, although, while water retention was present in this case, we convinced ourselves that the face appeared, and felt, more tense and " full " than before or afterwards. Evidence suggests that the symptoms are essentially due to hypotonicity of extracellular ,C~/'V,/Np'~.. fluid (Wynn and Garrod, 1955). These authors recommend that water-diuresis tests should be avoided unless the serum sodium is above 130 mEq/l.…”

Section: Commentmentioning

confidence: 99%

Case of Hypopituitary Coma with Serial Electroencephalography

Salmon¹

1956

BMJ

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Corticosteroid Therapy and Unintentional Camouflage

Christy

1988

JAMA

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suggests that medical reports should be interpreted in the light of performance in each treatment environment. If per¬ formance meets all expectations and measures well against known standards, methods should be changed only for good reasons; this is why we continue to use 1.5% formalin. Our experience indicates that change of methods leads to the appearance of unknowns; some may be good, but unantici¬ pated bad unknowns may result. The adverse environmental effects of formalin led to the development of other germicides for dialyzer processing. The CDC surveillance of 1350 US dialysis centers illustrates the appearance of an unanticipated adverse effect.! While there was no advantage in using renalin or glutaraldehyde, use of another germicide marketed as an alternative to formalin was associated with septicemia and an incidence of pyrogenic reactions much greater than previous¬ ly encountered. The data reported do not suggest any advan¬ tage in departing from the established germicide formalin.

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Spontaneous and Induced Water Intoxication in Two Cases of Hypopituitarism

Cited by 15 publications

References 11 publications

The Endocrinology of Pituitary Tumours

The Endocrinology of Pituitary Tumours

Case of Hypopituitary Coma with Serial Electroencephalography

Corticosteroid Therapy and Unintentional Camouflage

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