Spontaneous Descemet Membrane Detachment 20 Years After Penetrating Keratoplasty for Keratoconus

Gorski, Matthew; Shih, Carolyn; Savoie, Brian; Udell, Ira J.

doi:10.1097/ico.0000000000000873

Cited by 31 publications

(35 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…To our knowledge, this is the third case of spontaneous, late-onset DM detachment after uncomplicated PK to be reported in literature [5]. Previous reports involved two cases of spontaneous DM detachment, 21 and 25 years following penetrating keratoplasty for keratoconus.…”

Section: Discussionmentioning

confidence: 94%

Surgical management of spontaneous, late-onset Descemet membrane detachment after penetrating keratoplasty for keratoconus: a case report

et al. 2017

View full text Add to dashboard Cite

BackgroundTo report a surgical method for treating corneal oedema in a case of late-onset Descemet membrane detachment after penetrating keratoplasty.Case presentationA 55-year old patient presented with sudden visual loss in his left eye 28 years after penetrating keratoplasty for keratoconus. Slit-lamp biomicroscopy revealed a distortion of the corneal graft anatomy with protrusion of the graft and peripheral thinning and steepening in the residual host tissue, accompanied by corneal graft oedema. Anterior segment optical coherence tomography revealed detachment of Descemet membrane localized to the area of the graft oedema. We proceeded with a full-thickness, partially circumferential incision in the graft-host junction, followed by repositioning and re-suturing of the graft in place, and intracameral air injection in order to achieve reattachment of Descemet membrane.ConclusionsCorneal graft repositioning in combination with re-bubbling may represent an effective therapeutic option in keratoconic patients with peripheral thinning in the residual host corneal tissue and subsequent Descemet membrane detachment.

show abstract

Section: Discussionmentioning

confidence: 94%

Surgical management of spontaneous, late-onset Descemet membrane detachment after penetrating keratoplasty for keratoconus: a case report

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Delayed onset spontaneous DM detachment more than two decades after PK is a rare entitiy and sparsely documented in literature. [ 1 2 3 ] The cause of the DM detachment may be a recurrence of the primary pathology in case of keratoconus, or it could also be due to a mechanical cause like trauma to the eye. [ 1 ]…”

Section: Discussionmentioning

confidence: 99%

“…Descemet's membrane (DM) detachment leading to corneal edema in a postkeratoplasty eye is a rare entity especially when it occurs more than a decade after the surgery. [ 1 2 ] The possible reasons for this to occur could be a recurrence of the primary ectatic pathology in the corneal graft or secondary to even a trivial trauma to the operated eye. [ 1 ] In this case report, we discuss a case of spontaneous DM detachment 20-years after penetrating keratoplasty (PK).…”

mentioning

confidence: 99%

Late onset Descemet's membrane detachment 20 years after penetrating keratoplasty

D’Souza¹,

Solanki²,

Sushma³

et al. 2017

Indian J Ophthalmol

View full text Add to dashboard Cite

This paper reports a case of spontaneous Descemet's Membrane (DM) detachment 20-years after penetrating keratoplasty (PK). The patient presented with acute onset blurred vision in the right eye associated with mild ocular discomfort. There was no prior history of trauma. The patient had undergone PK in the right eye 20 years back. Detailed ophthalmic examination showed best corrected visual acuity of hand movements close to face in the right eye and 20/80 in the left eye. The right eye showed diffuse graft edema but no congestion, epithelial defect, or loss of continuity of graft-host junction to suggest a traumatic etiology. Anterior segment optical coherence tomography showed DM break with a detachment in the right eye, which was treated with an intracameral C3F8 injection. DM break with detachment post-PK has been very sparsely reported in literature and is an important differential to remember when faced with an edematous graft, in addition to the diagnosis of graft rejection or failure.

show abstract

“…OCT has led to the diagnosis of late Descemet's membrane detachment many years after a PK for keratoconus, in cases presenting with sudden onset of corneal oedema which may mistakenly be diagnosed as endothelial rejection or graft failure. In such cases, rebubbling of the Descemet's membrane with air in the anterior chamber can lead to clearing of the cornea without the need for a further transplant …”

Section: Corneal Transplantsmentioning

confidence: 99%

Optical coherence tomography imaging in keratoconus

Yip

Chan

2019

Clinical and Experimental Optometry

View full text Add to dashboard Cite

Optical coherence tomography (OCT) is being increasingly used as a tool in the diagnosis and management of keratoconus. While elevation-based topography remains essential, there is an expanding role for cross-sectional OCT imaging in the diagnosis of the disease. Images and measurements of corneal thickness, and in particular, epithelial thickness, may be important in diagnosing early cases, and following procedures such as intrastromal corneal ring segments, corneal transplants and corneal collagen cross-linking.

show abstract

Spontaneous Descemet Membrane Detachment 20 Years After Penetrating Keratoplasty for Keratoconus

Cited by 31 publications

References 8 publications

Surgical management of spontaneous, late-onset Descemet membrane detachment after penetrating keratoplasty for keratoconus: a case report

Surgical management of spontaneous, late-onset Descemet membrane detachment after penetrating keratoplasty for keratoconus: a case report

Late onset Descemet's membrane detachment 20 years after penetrating keratoplasty

Optical coherence tomography imaging in keratoconus

Contact Info

Product

Resources

About