Spontaneous gastric rupture after Sodium Bicarbonate consumption: A case report

Vásquez, Andrés; Domínguez, Carmen Carrillo; Perdomo, Carlos Felipe

doi:10.1016/j.radi.2017.03.019

Cited by 3 publications

(4 citation statements)

References 8 publications

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“…There are 10 cases reported in literature (including the two present cases) of gastric rupture associated with sodium bicarbonate ingestion since 1926. Apart from the case reported by Vasquez et al [48] in 2017, the last reported case was in 1989 [30].…”

Section: Demographicsmentioning

confidence: 88%

“…The lesser curvature is the weakest part of the muscular stomach wall due to the decreased number of mucosal folds [20,24,30]. As the stomach become distended, it assumes a spherical shape which stretches out the lesser curvature [24,48], causing local ischaemic necrosis and predisposing it to perforation [24]. The insertion of the gastro-hepatic ligament also results in relatively decreased mobility of the lesser curvature during distension [21,30], contributing to its propensity to rupture.…”

Section: Site Of Rupturementioning

confidence: 99%

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Binge-eating and sodium bicarbonate: a potent combination for gastric rupture in adults—two case reports and a review of literature

et al. 2022

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Background Disordered eating behaviour including binge-eating often results in significant medical conditions, which are at times fatal. It can result in acute gastric dilatation which can lead to ischemic necrosis and stomach rupture. Dyspepsia and bloating are common symptoms following binge eating. Patients commonly use over-the-counter medications like sodium bicarbonate or home remedies for relief. However, in very rare, reported cases, sodium bicarbonate has been attributed to cause acute gastric dilatation and spontaneous gastric rupture instead. Methods We report two cases of spontaneous gastric rupture following consumption of sodium bicarbonate containing antacids after a large meal, and a review of the literature of similar cases. Results A total of 36 cases were identified. Approximately half of the cases (47.2%) were correlated with eating disorders, with higher prevalence in females (69%) and a very high mortality rate (41.6%). Amongst the 36 cases, sodium bicarbonate ingestion was associated with 10 cases. The lesser curvature (36.1%) and anterior wall (33.3%) are the most common sites of rupture. Associated causes include binge-eating, gas release from sodium bicarbonate, gastric content fermentation, proximal and distal outlet obstruction, and muscular atony. Discussion Sudden distension and impaired emptying mechanism of the stomach is necessary for spontaneous gastric rupture to occur. Acute gastric dilatation with perforation requires definitive surgical management. There should be a low threshold of suspicion for patients presenting with severe abdominal pain and abdominal distension following an episode of binge-eating. There is a need for patient education around the use of over-the-counter medications or home remedies.

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Section: Demographicsmentioning

confidence: 88%

Section: Site Of Rupturementioning

confidence: 99%

Binge-eating and sodium bicarbonate: a potent combination for gastric rupture in adults—two case reports and a review of literature

et al. 2022

View full text Add to dashboard Cite

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“…The lesser curvature is the weakest part of the muscular stomach wall due to the decreased number of mucosal folds. [20,[28][29][30] As the stomach become distended, it assumes a spherical shape which stretches out the lesser curvature, [27,29] causing local ischaemic necrosis and predisposing it to perforation. [29] The insertion of the gastro-hepatic ligament also results in relatively decreased mobility of the lesser curvature during distension, [21,28] contributing to its propensity to rupture.…”

Section: Site Of Rupturementioning

confidence: 99%

“…[26] There are 10 cases reported in literature (including the two present cases) of gastric rupture associated with sodium bicarbonate ingestion since 1926. Apart from the case reported by Vasquez et al in 2017,[27] the last reported case was in 1989. [28]…”

mentioning

confidence: 97%

Binge-eating and Sodium Bicarbonate: A potent combination for gastric rupture in adults. Two case reports and a review of literature

Han

Roy

Siau

et al. 2022

Preprint

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Background – Disordered eating behaviour including binge-eating often results in significant medical conditions, which are at times fatal. It can result in acute gastric dilatation which can lead to ischemic necrosis and stomach rupture. Dyspepsia and bloating are common symptoms following binge eating. Patients commonly use over-the-counter medications like sodium bicarbonate or home remedies for relief. However, in very rare, reported cases, sodium bicarbonate has been attributed to cause acute gastric dilatation and spontaneous gastric rupture instead. Methods – We report two cases of spontaneous gastric rupture following consumption of sodium bicarbonate containing antacids after a large meal, and a review of the literature of similar cases. Results – A total of 36 cases were identified. Approximately half of the cases (47.2%) were correlated with eating disorders, with higher prevalence in females (69%) and a very high mortality rate (41.6%). Amongst the 36 cases, sodium bicarbonate ingestion was associated with 10 cases. The lesser curvature (36.1%) and anterior wall (33.3%) are the most common sites of rupture. Associated causes include binge-eating, gas release from sodium bicarbonate, gastric content fermentation, proximal and distal outlet obstruction, and muscular atony. Discussion – Sudden distension and impaired emptying mechanism of the stomach is necessary for spontaneous gastric rupture to occur. Acute gastric dilatation with perforation requires definitive surgical management. There should be a low threshold of suspicion for patients presenting with severe abdominal pain and abdominal distension following an episode of binge-eating. There is a need for patient education around the use of over-the-counter medications or home remedies.

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