Spontaneous resolution of a branchial cleft cyst without intervention: a previously unreported outcome

Brennan, Peter A.; Critchlow, Angela; Rehman, Sara; Thomas, Deepak

doi:10.1016/j.bjoms.2014.02.004

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…This study was performed to provide an answer to the hypothesis that estrogen is able to induce epithelial proliferation in branchial cleft cysts, thus leading to their enlargement during pregnancy as observed in three consecutive cases. This theory was supported by the report of a patient with an enlargement of a branchial cleft cyst after child-birth followed by spontaneous resolution without intervention, perhaps as a result of the hormonal changes that occur after pregnancy [ 6 ].…”

Section: Discussionmentioning

confidence: 92%

Possible Estrogen Dependency in the Pathogenesis of Branchial Cleft Cysts

Raguse

Anagnostopoulos

Doll

et al. 2017

BioMed Research International

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Background Even though branchial cleft cysts are currently accepted as a congenital anomaly, there is often a long delay until clinical presentation; branchial cleft cysts classically appear in the second to fourth decade of life. Our observation of their occurrence in three pregnant women encouraged us to contemplate a possible hormonal influence. Methods Immunohistological analysis was performed for the evaluation of the estrogen receptor alpha (ERα) in paraffin-embedded tissue specimens of 16 patients with a diagnosis of branchial cleft cyst, with three of them being pregnant. Results Expression of ERα was detected within epithelial cells only in branchial cleft cysts in pregnant females; moreover, higher growth fractions (Ki-67/Mib1) were found. Conclusion The fact that the estrogen receptor was expressed only in pregnant women, in contrast to 13 investigated cases, may suggest that the high level of estrogen in pregnancy is a possible explanation for the spontaneous growth of branchial cleft cysts.

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Section: Discussionmentioning

confidence: 92%

Possible Estrogen Dependency in the Pathogenesis of Branchial Cleft Cysts

Raguse

Anagnostopoulos

Doll

et al. 2017

BioMed Research International

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A case of a giant Bailey type I lateral cervical cyst

Seki,

Nishiura,

Kishino

et al. 2024

Oral Science International

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BackgroundLateral cervical cysts are among the most frequent branchial anomalies of the neck, although they rarely become large.Case presentationThe present case involved a 32‐year‐old man with swelling of the right side of the neck. Pre‐operative CT findings showed a low CT value on the right side of the neck. Lateral cervical cyst removal was performed under general anesthesia, and the excision was 100 mm × 70 mm × 30 mm, which is the largest ever reported removal of a Bailey type I lateral cervical cyst.ConclusionThe patient had a good clinical course, with no post‐operative recurrence.

show abstract

Spontaneous resolution of a branchial cleft cyst without intervention: a previously unreported outcome

Cited by 2 publications

References 9 publications

Possible Estrogen Dependency in the Pathogenesis of Branchial Cleft Cysts

Possible Estrogen Dependency in the Pathogenesis of Branchial Cleft Cysts

A case of a giant Bailey type I lateral cervical cyst

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