Spontaneous twin pregnancy with live births after cryopreservation and re-implantation of ovarian tissue

Milenković, Milan; Brännström, Mats; Díaz-García, César; Lundin, Kersti; Selleskog, Ulrika; Söderlund, Brita; Khatibi, Ali; Gull, Berit; Bokström, Hans; Mateoiu, Constantina; Akyürek, Levent M.; Thurin‐Kjellberg, Ann

doi:10.1186/s10397-017-1012-6

Cited by 8 publications

(3 citation statements)

References 7 publications

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“…2). Hereof, 81 singleton pregnancies and 6 twin pregnancies [14,20,26,46,78,83] with 10 pregnancies ongoing [10,12,14,22,[26][27][28]57] (Danish cohort) from which 7 women will have their first child.…”

Section: Pregnancies and Live Birthsmentioning

confidence: 99%

Transplantation of frozen-thawed ovarian tissue: an update on worldwide activity published in peer-reviewed papers and on the Danish cohort

Gellert

Pors

Kristensen

et al. 2018

J Assist Reprod Genet

243

204

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This study found no indications of sufficient numbers of malignant cells present in the ovarian tissue to cause recurrence of cancer after OTT. Further, it is unlikely that OTC affects the well-being of children born. OTC is now an established method of fertility preservation in Denmark with public reimbursement. The current data encourage that women who require gonadotoxic treatment should be offered an individual evaluation considering fertility preservation.

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Section: Pregnancies and Live Birthsmentioning

confidence: 99%

Transplantation of frozen-thawed ovarian tissue: an update on worldwide activity published in peer-reviewed papers and on the Danish cohort

Gellert

Pors

Kristensen

et al. 2018

J Assist Reprod Genet

243

204

View full text Add to dashboard Cite

show abstract

“…The efficacy of the method is reduced by the detrimental effects caused via cryopreservation as well as ischemia-reperfusion injury at re-transplantation, but globally, the number of children born after successful re-transplantation is increasing [ 39 , 70 , 71 , 72 ]. The success rate of ovarian tissue freezing is dependent on a good ovarian reserve, and re-transplantation has been more effective in young women and girls.…”

Section: Fertility Preservation As An Acute Measurementioning

confidence: 99%

The Late Effects of Cancer Treatment on Female Fertility and the Current Status of Fertility Preservation—A Narrative Review

Rodriguez‐Wallberg

Jiang

Lekberg

et al. 2023

Life

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Fertility counseling should be offered to all individuals of young reproductive age early in the patient’s trajectory following a cancer diagnosis. Systemic cancer treatment and radiotherapy often have an inherent gonadotoxic effect with the potential to induce permanent infertility and premature ovarian failure. For the best chances to preserve a patient’s fertility potential and to improve future quality of life, fertility preservation methods should be applied before cancer treatment initiation, thus multidisciplinary team-work and timely referral to reproductive medicine centers specialized in fertility preservation is recommended. We aim to review the current clinical possibilities for fertility preservation and summarize how infertility, as a late effect of gonadotoxic treatment, affects the growing population of young female cancer survivors.

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“…Scientific evidence estimates a total of 143 pregnancies which were noted in 103 patients, counting in both biochemical and clinical pregnancies. This resulted in 98 live births by 76 women, and a total of 94 children born [3,5,14,17,20,[29][30][31][32][33][34][35][36]. The mean age of patients achieving live birth (LB) or ongoing pregnancy (OGP) (26.4 years (SD 6.3), range 9-38 years) was significantly lower at OTC (P value = 0.0019) compared to patients who failed to conceive (29.6 years (SD 5.4), range 14-39 years) [19].…”

Section: Pregnancies and Live Births (Lbs)mentioning

confidence: 99%

Ovarian Cryopreservation: An Overview of Current Evidence around the Globe

Gkrozou¹,

Tsonis²

2021

COGO

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Advancements in cancer as well as, autoimmunological or hematological conditions treatment have significantly increased the survival rate as well as, the Quality of Life (QoL) for these patients. In addition, Assisted Reproductive Techniques (ART) offers a variety of therapeutic approaches that aim towards fertility preservation and hormonal restoration after treatment. Ovarian Tissue Cryopreservation (OTC) and Ovarian Tissue Transplantation (OTT) have been proposed as an efficient alternative to reserve fertility and hormona function in cases of prepubertal young girls and women needed to be treated immediately with radiation and/or chemotherapy. In this narrative review, current scientific evidence is summarized in order to explore OTC/OTT. In addition to the qualitive presentation of our findings, we provide cumulative evidence from other published studies to demonstrate the clinical potential and limitations of these procedures.

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Spontaneous twin pregnancy with live births after cryopreservation and re-implantation of ovarian tissue

Cited by 8 publications

References 7 publications

Transplantation of frozen-thawed ovarian tissue: an update on worldwide activity published in peer-reviewed papers and on the Danish cohort

Transplantation of frozen-thawed ovarian tissue: an update on worldwide activity published in peer-reviewed papers and on the Danish cohort

The Late Effects of Cancer Treatment on Female Fertility and the Current Status of Fertility Preservation—A Narrative Review

Ovarian Cryopreservation: An Overview of Current Evidence around the Globe

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