Spontaneous vesicle formation and vesicle–tubular microstructure transition in aqueous solution of a poly-tailed cationic and anionic surfactants mixture

Zwitterionic betaine-cholesterol system: Effects of sonication duration and aging on vesicles stability

“…In the single phase region, the appearance and birefringence under cross polarization of the zwitterionic betaine/cholesterol dispersant mixture (Fig.1 insets) varied between colourless transparent, bluish transparent, and bluish turbid. Colourless transparent solution indicate that the formation of micelles dominate, while bluish transparent appearance signifies successful vesicle formation [15,16,21] with low polydispersity (~0.2), and supported by our TEM results. Additionally, the dispersion turbidity increased relative to increased total concentration and ratios of zwitterionic betaine/cholesterol due to increased polydispersity (DLS results).…”

“…The metastable structure of liposomes [11,12] increases susceptibility to aggregation, fusion, or content leakage during storage in aqueous suspensions [13,14]. Of increasing interest are methods allowing creation of non-lipid vesicles in order to enhance liposomal stability [1,15]. Combinations of surfactant mixtures [16][17][18][19][20] have been used to initiate assembly and increase the thermodynamic stability of vesicles under different environmental conditions, including aging time, temperature, pH, and pressure [20][21][22][23].…”

Aggregation behavior in mixed system of double-chained anionic surfactant with single-chained nonionic surfactant in aqueous solution

“…Small values of P predict the formation of spherical micelles (P < 1/3) and cylindrical micelles (1/3 < P 1/2), while vesicles or bilayers form when 1/2 < P 1. The ethyl branch at the second carbon of the hydrophobic chains and the preponderant trans and gauche conformations of AOT may lead its P value very close to 1 [29,30]. This means that AOT molecule may look like a cylinder.…”

Morphological transformation of self-assembled nanostructures prepared from cholesteryl acyl didanosine and the optimal formulation of nanoparticulate systems: Effects of solvents, acyl chain length and poloxamer 188

“…The poly-tailed cationic and anionic surfactants mixture of tri-(N-dodecyldimethylhydroxypropylammonium chloride) phosphate and bis-(2-ethylhexyl) sulfosuccinate forms spherical vesicles spontaneously in aqueous solution. However, along with the increase of surfactant concentration, spherical vesicles begin to fuse and transform ultimately into tubular vesicles [25]. Micelles of cetyltrimethylammonium bromide (CTAB), when doped with increasing levels of 4-ethylphenol, show microstructural transitions from spherical micelles to elongated wormlike micelles, disks, and subsequently to globular and then to tubular vesicles [26].…”