Spread of multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa clones in patients with ventilator-associated pneumonia in an adult intensive care unit at a university hospital

Abstract

These findings suggest the requirement of constant monitoring of these microorganisms in order to control the spread of these clones in the hospital environment.

Multidrug-resistant bacteria isolated from patients hospitalized in Intensive Care Unit in University Hospital of Constantine, Algeria (2011 - 2015)

“…The risk of acquiring MDR bacteria in the ICU is increased by severity of illness, length of stay, use of intravascular devices, exposure of ICU patients to invasive therapeutic procedures like endotracheal intubation, the intensity of exposure to infected patients and the frequent misuse of antibiotic drug (Khan et al, 2014;Royer et al 2015;Wroblewska et al, 2006).…”

Pseudomonas infections among hospitalized adults in Latin America: a systematic review and meta-analysis

“…The most frequently assessed antibiotics included carbapenem and aminoglycosides (Supplemental Table 5). All of the examined predictors were reported as significant predictors for acquisition of resistant P. aeruginosa except for the following in three studies: Acute Physiology And Chronic Health Evaluation II (APACHE II) and hospital stay (1 study [20]), heart failure as a co-occurring disease (1 study [21]), and number of antibiotics used (1 study [24]).…”

“…The literature search identified a total of 165 citations; of which, 98 full-text articles were retrieved and assessed for eligibility. The systematic review included 19 articles (6 articles for AIAT versus IIAT [12][13][14][15][16][17]; 17 articles for acquisition of resistant or multidrug-resistant P. aeruginosa [12,[14][15][16][18][19][20][21][22][23][24][25][26][27][28][29][30] and 4 articles reported both outcomes [12,[14][15][16]) that met final eligibility criteria ( Fig. 1).…”

“…Nineteen studies reported in 17 articles (two articles contributed to four studies) were included (Table 3) [12,[14][15][16][18][19][20][21][22][23][24][25][26][27][28][29][30]. A total of 3203 total subjects (1077 cases and 2126 controls) were examined for risk factors of acquisition of [29]).…”

Estudo Multicêntrico de Infecções Relacionadas à Assistência à Saúde em Unidades de Terapia Intensiva de Adultos no Estado de Minas Gerais, Brasil

“…Estudos brasileiros avaliaram a epidemiologia de IRAS em UTI causada por micro-organismos multirresistentes e os resultados indicaram que essas infecções são altamente prevalentes, principalmente aquelas causadas por Klebsiella pneumoniae produtora de carbapenemase (KCP), Acinetobacter baumannii e Pseudomonas aeruginosa resistentes a carbapenêmicos (SADER et al, 2001;GALES et al, 2012;ROYER et al, 2015;ROSSI GONÇALVES et al, 2016 Antibiograma Antimicrobiano IRAS 1 IRAS 2 IRAS 3 MIC 1 MIC 2 MIC 3 MIC 1 MIC 2 MIC 3 MIC 1 MIC 2 Esperamos contar com a aprovação para a realização do projeto junto a vossa instituição, permaneço à disposição para o envio de outras informações que julgar relevantes.…”