Spreading cortical venous thrombosis due to infusion of hyperosmolar solution into the internal jugular vein.

Comparison of Central Venous Catheterization Sites in Infants

“…A malpositioned central venous catheter may lead to incorrect measurement of central venous pressure and also cause more serious complications such as thrombosis and thrombophlebitis, 18,22 specifically cerebral venous thrombosis, 23,24 when located in the IJV. In this regard, our results suggest that the SCV may not be a safe choice for catheterization in infants.…”

Cerebral venous and sinus thrombosis – an update

“…Local causes for CVST may be head injury (Barnett and Hyland, 1953;Kalbag and Woolf, 1967;Bousser et al, 1985;Thron et al, 1986) or catheterization of the internal jugular vein (Souter and Mitchell, 1982; Stephens er al., 1991).…”

Fatal Septic Internal Jugular Vein-Sigmoid Sinus Thrombosis Associated with a Malpositioned Central Venous Catheter

“…The reported incidence of primary misplacement of the catheter tip after infraclavicular subclavian vein catheterization varies from 5% to 24% even when inserted by experienced clinicians7). Inadvertent catheterization of the ipsilateral internal jugular vein is one of the most common misplacements, with a reported incidence of around 7%15). Malpositioned catheters may lead to serious complications.…”

“…Also, positioning of the catheter tip in the subclavian vein is associated with a high risk of thrombus formation and vessel occlusion2). The risk of thrombosis may increase when hyperosmolar parenteral nutrition fluid is administered through a misplaced central venous catheter into a internal jugular vein3,15). Moreover, malpositioned catheter tips can damage the endothelium and precipitate the formation of thrombi17).…”

“…Three reports describe an association between cerebral venous sinus thrombosis and central venous hyperalimentation due to placement of the catheter tip in the internal jugular vein3,15,16). The authors warn of the potential for thrombosis due to retrograde infusion into the valveless internal jugular-dural sinus system but also suggest that the small caliber of the vein may predispose to thrombosis.…”