“…In Japan, Murakami et al described the first case of a pure SCC of the colon in 1974 [13]. It has been suggested that a number of criteria must be satisfied before a diagnosis of primary squamous cell carcinoma of the large bowel is entertained [3,14,15]: (1) there must be no evidence in any other organ of a squamous cell carcinoma that might spread directly into the lower bowel or provide a source of intestinal metastases, (2) the affected bowel should not be involved in a fistulous tract lined with squamous cells (colocutaneous fistulas have been described in association with squamous cell cancer), (3) when squamous cell carcinoma occurs in the rectum, care must be taken to exclude origin from the anal canal (that is, there should be a lack of continuity between the lesion and the anal canal epithelium), and (4) SCC must be confirmed by histological analysis. Our case satisfied all the above criteria.…”