Squamous Cell Carcinoma of the Lacrimal Sac: A Case and Literature Review

Duman, Rahmi; Ceyda, Başkan; Mehmet, Balci; Özdoğan, Sibel; Akdulum, İsmail

doi:10.9734/or/2014/9904

Cited by 2 publications

(3 citation statements)

References 13 publications

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“…Cases of squamous cell carcinoma of the lacrimal sac have been reported all over the world. 1 , 2 , 3 , 4 Several reports specific to SCC are available, 4 , 5 as are several literature reviews referring to the more general category of epithelial neoplasms of the lacrimal sac. 3 , 6 , 7 An estimated 300–775 lacrimal sac tumors have been reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

“…Lacrimal sac tumors typically present with symptoms of lacrimal duct obstruction and can easily be misdiagnosed as dacryocystitis during initial encounters. 5 To differentiate, inflammation in chronic dacryocystitis often occurs below the medial canthal tendon whereas lacrimal sac tumors may occur above or below the tendon. 10 Presenting symptoms include pain and epiphora (with or without spontaneous retrocanalicular bleeding).…”

Section: Discussionmentioning

confidence: 99%

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Complete resolution of a large squamous cell carcinoma of the lacrimal duct in a young African American male after non-surgical management

Kanyinda

Soni

Ramadan

et al. 2020

American Journal of Ophthalmology Case Reports

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Purpose The following case describes a 28-year old African American male who presented with squamous cell carcinoma of the lacrimal duct. Despite its size and location, his tumor showed complete resolution with non-surgical treatment. Observations The patient presented with a 4-month history of dacryocystitis-like symptoms in the right eye, with no prior medical history and a history of tobacco smoking. Pathology indicated that SCC arose as nests within a benign sinonasal inverted papilloma. He received cisplatin chemotherapy and radiotherapy with tumor resolution in 4 months. Several months after the end of treatment, he experienced irreversible visual deterioration which led to enucleation of the right eye. The patient has remained in remission for 4 years following the treatment. Conclusions The complete resolution of the mass with non-surgical management supports the most recent literature endorsing a multidisciplinary approach for localized tumors. Our patient is the only African American identified in the literature and the youngest reported patient to present with this tumor. Most case studies have not emphasized race, ethnicity and demographics, although it is known that morbidity in malignancy is impacted by these factors.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Complete resolution of a large squamous cell carcinoma of the lacrimal duct in a young African American male after non-surgical management

Kanyinda

Soni

Ramadan

et al. 2020

American Journal of Ophthalmology Case Reports

View full text Add to dashboard Cite

show abstract

“…Metastases are late occurrences, and whilst the level of node involved is typical, the contralateral site is not. 11 The contralateral tonsillar SCC could also have been a metastasis, however this has never been previously published and the location makes this improbable. It is also possible that the multiple previous DCR operations seeded the primary sac tumour.…”

Section: Commentmentioning

confidence: 96%