Squamous cell carcinoma of the nasal vestibule: a 20-year case series and literature review

Dowley, Andrew; Hoskison, Emma; Allibone, R; Jones, Nick

doi:10.1017/s0022215108002259

Cited by 47 publications

(35 citation statements)

References 16 publications

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“…Despite advances in reconstructive surgery and maxillofacial prosthetics in recent years, surgery as the primary treatment modality is still not preferred in such T3 lesions . There is a perception among both patients and physicians that radical surgery with reconstruction (surgical or prosthetic) is disfiguring and that RT achieves a better cosmetic result . However, reconstructive surgery and maxillofacial prosthetics have made considerable progress, with excellent cosmetic results.…”

Section: Discussionmentioning

confidence: 99%

Irradiation of localized squamous cell carcinoma of the nasal vestibule

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Irradiation of localized squamous cell carcinoma of the nasal vestibule

et al. 2015

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“…The incidence of reported positive nodes in SCCNV is depicted in Table I. [4][5][6]11,12,16,[18][19][20][21][22][23][24][25][26][27][28][29]31,34,35 CONCLUSION SCCNV cancer is an uncommon isolated form of cancer, possibly originating in the mucocutaneous junction and is usually smoking induced. The incidence of synchronous or delayed regional metastases is higher than 20% in about half of the reported series.…”

Section: Discussionmentioning

confidence: 99%

“…Five-year recurrence-free survival rates range widely between 20% and 92%. [4][5][6] Early detection of these lesions warrants a high index of suspicion because they are often initially misdiagnosed.…”

mentioning

confidence: 99%

Lymph node metastasis in nasal vestibule cancer: A review

et al. 2010

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“…However, their prognosis remains better compared with that of other sinonasal malignant tumors, such as maxillary sinus and frontal sinus malignant tumor (13,14). The 5-year recurrence-free survival rates range widely between 20 and 92% (15)(16)(17).…”

Section: Discussionmentioning

confidence: 99%

Synchronous double primary cancer of the lung and nasal vestibule: A case report and literature review

Zang

Wang

et al. 2016

Molecular and Clinical Oncology

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Abstract. Squamous cell carcinoma (SCC) of the nasal vestibule is a rare tumor entity, and its occurrence combined with lung cancer is even rarer. Thus, several patients are often initially misdiagnosed or remain undiagnosed. This is the case report of a 55-year-old male patient who presented to our hospital with a neoplasm in the left lung. The patient was treated with left upper pulmonary lobectomy and the subsequent histopathological examination of the surgical specimen revealed a poorly differentiated SCC. On postoperative week 4, the patient presented with purulent and bloody discharge from the left nostril and was misdiagnosed with an upper jaw cyst. After another 3 weeks, the patient was re-admitted to the hospital with a mass of left nostril and nasal congestion. Tru-Cut biopsies from the nasal area and histopathological examination revealed a moderately differentiated SCC. According to the clinical presentation and the histopathological findings, the patient was diagnosed with double primary cancer of the lung and the nasal vestibule. The mass of the left nostril was significantly reduced in size with radiotherapy. To the best of our knowledge, there is no similar case previously reported in the literature. Due to the rarity of SCC of the nasal vestibule concomittant with lung cancer, we herein present this case report with a review of the relevant literature and investigation of the clinical characteristics. IntroductionMultiple primary cancers are defined as ≥2 separate original cancers, simultaneously or successively occurring in the same or different organs. Double primary cancer is the most common type of multiple primary cancer and it is classified as synchronous carcinoma (SC) and metachronous carcinoma (MC). SC is used to describe the second primary tumor when it is diagnosed simultaneously or within 6 months of the diagnosis of the first primary tumor. MC is is used to describe the second cancer when it is diagnosed >6 months after the first primary cancer (1). The first double primary cancer was reported in 1889 by Billroth (2), whose standard of the diagnosis was that each tumor should have a different localization and independent histological appearance. In 1932, Warren and Gates established new criteria, which are still applied today: i) Both cancers must be definitively malignant according to the histopathological examination; ii) the cancers must be histologically different; and iii) it must be established that the second cancer is not a metastatic lesion of the first (3). The incidence of multiple primary cancers appears to have increased significantly. Approximately 10% of cancer patients develop another primary cancer within 10 years of the first surgery (4). However, double primary cancer of the lung and nasal vestibule is uncommon. We herein describe an extremely rare case of synchronous double primary cancer involving the left nasal vestibule and the left lung, with a review of the literature. Case reportA 55-year-old man presented to the Qianfoshan Hospital on April 8, 2015, where ...

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Squamous cell carcinoma of the nasal vestibule: a 20-year case series and literature review

Cited by 47 publications

References 16 publications

Irradiation of localized squamous cell carcinoma of the nasal vestibule

Irradiation of localized squamous cell carcinoma of the nasal vestibule

Lymph node metastasis in nasal vestibule cancer: A review

Synchronous double primary cancer of the lung and nasal vestibule: A case report and literature review

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