Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes

Matić, Tamara; Zebic, Maja Lezaja; Miletić, Vesna; Cvijović‐Alagić, Ivana; Petrović, Rada; Janaćković, Dj.; Veljović, Djordje

doi:10.1016/j.ceramint.2021.12.335

Cited by 10 publications

(13 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There are limited literature data on the effects of HAP inserts on tooth restorations. [9][10][11]24,36 To the best of our knowledge, there have been no studies to date that investigate fracture resistance of human teeth restored with HAP based dental inserts. Further testing is required to ascertain the effects of other cavity types and insert-restorative material combinations on FR of restored teeth.…”

Section: Discussionmentioning

confidence: 99%

“…The Mg‐ and Sr‐ substituted HAP nanoparticles were synthesized by using the modified hydrothermal method previously described elsewhere 24 . Precursor solutions were thermally treated in an autoclave at two different conditions: T = 150°C, p = 6 bar, t = 3 h (denoted as Mg6 and Sr6) T = 160°C, p = 8 bar, t = 3 h (denoted as Mg8). …”

Section: Methodsmentioning

confidence: 99%

“…The Mg-and Sr-substituted HAP nanoparticles were synthesized by using the modified hydrothermal method previously described elsewhere. 24 Precursor solutions were thermally treated in an autoclave at two different conditions: Although the same nominal amount of ions was used during synthesis, higher pressure applied during synthesis led to somewhat increased Mg content in the Mg-HAP powders, as well as higher content of Sr ions in Sr-HAP compared to Mg ions in Mg-HAP powders (Table 1).…”

Section: Preparation and Characterization Of Mg-and Sr-substituted Ha...mentioning

confidence: 99%

“…Detailed characterization of the starting powders and sintered compacts used in this study are given in our previous publications. 24,25 The phase composition of doped HAP based dental inserts was determined by X-ray diffraction (XRD), conducted on X-ray A field emission scanning electron microscope (SEM) (Tescan FE-SEM Mira 3 XMU) operated at 20 keV was engaged for evaluation of the inserts' surfaces microstructure upon etching with 37% phosphoric acid for 15 s (Scotchbond Universal Etchant, 3M ESPE). Prior to the SEM analysis, all samples were coated with thin layer of gold using a sputter coater (Polaron SC503, Fisons Instruments).…”

Section: Preparation and Characterization Of Mg-and Sr-substituted Ha...mentioning

confidence: 99%

“…Abbreviations: HAP, hydroxyapatite; α or β-TCP, α or β-tricalcium phosphate. a Data shown for comparison purposes, published in Reference[24].…”

mentioning

confidence: 99%

See 4 more Smart Citations

Hydroxyapatite‐based dental inserts: Microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations

Matic,

Zebic,

Miletic

et al. 2023

J Biomed Mater Res

View full text Add to dashboard Cite

This study aimed to (1) comparatively analyze properties of Sr‐ and Mg‐substituted hydroxyapatite (HAP)‐based dental inserts; (2) evaluate insert bonding to restorative materials, and (3) evaluate the effect of doped HAP inserts on fracture resistance (FR) of human molars with large occlusal restorations. By ion‐doping with Sr or Mg, 3 insert types were obtained and characterized using XRD, SEM, Vickers hardness and fracture toughness. Shear bond strength (SBS) was determined between acid etched or unetched inserts and following materials: Maxcem cement (Kerr); Filtek Z250 (3M) bonded with Single Bond Universal (SBU; 3M) or Clearfil Universal (Cf; Kuraray). Modified Class I cavities were prepared in 16 intact molars and restored using insert + composite or composite only (control) (n = 8/group). FR of restored molars was determined by static load until fracture upon thermal cycling. Fracture toughness was similar between Sr/Mg‐doped inserts (0.94–1.04 MPam−1/2 p = .429). Mg‐doped inserts showed greater hardness (range 4.78–5.15 GPa) than Sr6 inserts (3.74 ± 0.31 GPa; p < .05). SBS for SBU and Cf adhesives (range 7.19–15.93 MPa) was higher than for Maxcem (range 3.07–5.95 MPa) (p < .05). There was no significant difference in FR between molars restored with insert‐containing and control restorations (3.00 ± 0.30 kN and 3.22 ± 0.42 kN, respectively; p > .05). HAP‐based inserts doped with Mg/Sr had different composition and mechanical properties. Adhesive bonding to inserts resulted in greater bond strength than cementation, which may be improved by insert acid‐etching. Ion‐doped HAP inserts did not affect FR of restored molars. In conclusion, HAP‐based dental inserts may potentially replace dentin in large cavities, without affecting fracture resistance of restored teeth.

show abstract