This paper describes the stability and Hopf bifurcation analysis of the Brusselator system with delayed feedback control in the single domain of a reaction–diffusion cell. The Galerkin analytical technique is used to present a system equation composed of ordinary differential equations. The condition able to determine the Hopf bifurcation point is found. Full maps of the Hopf bifurcation regions for the interacting chemical species are shown and discussed, indicating that the time delay, feedback control, and diffusion parameters can play a significant and important role in the stability dynamics of the two concentration reactants in the system. As a result, these parameters can be changed to destabilize the model. The results show that the Hopf bifurcation points for chemical control increase as the feedback parameters increase, whereas the Hopf bifurcation points decrease when the diffusion parameters increase. Bifurcation diagrams with examples of periodic oscillation and phase-plane maps are provided to confirm all the outcomes calculated in the model. The benefits and accuracy of this work show that there is excellent agreement between the analytical results and numerical simulation scheme for all the figures and examples that are illustrated.