Stable changes in the pattern of the recruiting response associated with a well established conditioned reflex

Sakhiulina, G. T.; Merzhanova, G. Kh.

doi:10.1016/0013-4694(66)90140-4

Cited by 18 publications

(3 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Certain types of secondary responses associated with complex brain functions are influenced by barbiturate resulting in either reduced or abolished activity (Fuster and Docter, 1962 ; Torres and Warner, 1962 ). These responses are correlated with activation of the mesencephalic reticular formation (Fuster and Docter, 1962 ; Torres and Warner, 1962 ) and are related to memory (John, 1967 ) and passive or active conditioning (Sakhiulina and Merzhanova, 1966 ; Fox, 1970 ). It is also believed that the FC, the centro-parietal cortex, and the hippocampus are possible generators for late components (Santos Filha and Matas, 2010 ).…”

Section: Discussionmentioning

confidence: 99%

Quantification of mid and late evoked sinks in laminar current source density profiles of columns in the primary auditory cortex

Schaefer

Hechavarría

Kössl

2015

Front. Neural Circuits

View full text Add to dashboard Cite

Current source density (CSD) analysis assesses spatiotemporal synaptic activations at somatic and/or dendritic levels in the form of depolarizing current sinks. Whereas many studies have focused on the short (<50 ms) latency sinks, associated with thalamocortical projections, sinks with longer latencies have received less attention. Here, we analyzed laminar CSD patterns for the first 600 ms after stimulus onset in the primary auditory cortex of Mongolian gerbils. By applying an algorithm for contour calculation, three distinct mid and four late evoked sinks were identified in layers I, III, Va, VIa, and VIb. Our results further showed that the patterns of intracortical information-flow remained qualitatively similar for low and for high sound pressure level stimuli at the characteristic frequency (CF) as well as for stimuli ± 1 octave from CF. There were, however, differences associated with the strength, vertical extent, onset latency, and duration of the sinks for the four stimulation paradigms used. Stimuli one octave above the most sensitive frequency evoked a new, and quite reliable, sink in layer Va whereas low level stimulation led to the disappearance of the layer VIb sink. These data indicate the presence of input sources specifically activated in response to level and/or frequency parameters. Furthermore, spectral integration above vs. below the CF of neurons is asymmetric as illustrated by CSD profiles. These results are important because synaptic feedback associated with mid and late sinks—beginning at 50 ms post stimulus latency—is likely crucial for response modulation resulting from higher order processes like memory, learning or cognitive control.

show abstract

Section: Discussionmentioning

confidence: 99%

Quantification of mid and late evoked sinks in laminar current source density profiles of columns in the primary auditory cortex

Schaefer

Hechavarría

Kössl

2015

Front. Neural Circuits

View full text Add to dashboard Cite

show abstract

“…Sakhiulina and Merzhanova (1966) observed slow surface negative waves in the operant motor zone following establishment of a conditional reflex to low frequency stimulation of midline thalamic nuclei in cats, and Wurtz (1966) has reported similar effects in self-stimulation experiments with rats. Low et al (1966a, b) have demonstrated surface negative slow potential shifts during operant conditioning in rhesus monkeys and regard these as identical with the human CNV.…”

mentioning

confidence: 85%

Contingent negative variation and evoked responses recorded by radio-telemetry in free-ranging subjects

Walter

Cooper

Crow

et al. 1967

Electroencephalography and Clinical Neurophysiology

View full text Add to dashboard Cite

“…In all cases when the conditioned reflex was being established, the natural manifestation of the conditioned-reflex reaction preceded its electrophysiological manifestation, which gives evidence that the appear ance of the additional complex of waves is bound to the period of locali zation of the conditioned reflex [A sratyan, 1965, 1967] as well as to the functioning of well-established conditioned reflexes [Sakhiulina and M erzanova, 1964[Sakhiulina and M erzanova, , 1965[Sakhiulina and M erzanova, , 1966Sakhiulina and L ubchinsky, 1968], However, it was evident from the experiments that the additional RR complex appeared only after long training of an already localized condi tioned reflex.…”

Section: Discussionmentioning

confidence: 99%

Electrophysiological Analysis of Conditioned Reflexes where the Conditional Stimulus is the Stimulation of Phylogenetically Different Parts of the Cerebellum

Vv¹,

Ev²

1974

Brain Behav Evol

View full text Add to dashboard Cite

The production of a food-procuring conditioned reflex to the stimulation of phylogenetically different nuclei of the cerebellum was shown in cats. A correlation was shown between the electrophysiological and behavioral indices of food-procuring conditioned reflexes. Changes in the recruiting-like potentials recorded from the cerebral cortex were found to the low-frequency stimulation of the nuclei dentatus and interpositus, the stimulation being used as a positive conditional stimulus. It was shown that the phylogenetically different nuclei of the cerebellum are functionally heterogeneous. The development of conditioning and conditioned inhibition, produced to different parameters of stimulation to the cerebellar nuclei, showed mainly the inhibitory possibilities of the cerebellar projections to the forebrain through the nonspecific thalamic structures as well as the activating nature of the cerebellar influences through the reticular formation of the midbrain.

show abstract

Stable changes in the pattern of the recruiting response associated with a well established conditioned reflex

Cited by 18 publications

References 13 publications

Quantification of mid and late evoked sinks in laminar current source density profiles of columns in the primary auditory cortex

Quantification of mid and late evoked sinks in laminar current source density profiles of columns in the primary auditory cortex

Contingent negative variation and evoked responses recorded by radio-telemetry in free-ranging subjects

Electrophysiological Analysis of Conditioned Reflexes where the Conditional Stimulus is the Stimulation of Phylogenetically Different Parts of the Cerebellum

Contact Info

Product

Resources

About