Dr. Gray, a critical care specialist in a rural emergency room, was evaluating Mrs. Mason. The 80-year-old wife and grandmother, accompanied by her daughter Sarah, had been brought in by ambulance after body aches, fever, and persistent coughing of a day's duration turned into extreme shortness of breath and shaking chills. She was febrile and had tachycardia, low blood pressure, and dangerously low oxygen saturation. A chest x-ray demonstrated a significant, severe pneumonia. In keeping with a desire previously expressed to her husband and children to "do everything," she was intubated and transferred to the hospital's four-bed intensive care unit where she received IV fluids and antibiotics. Her vital signs returned to normal on the higher level of support. Dr. Gray began preparing to sign out for the evening at 7 o'clock. Mrs. Mason remained intubated but appeared clinically stable. Dr. Gray anticipated that she might have the breathing tube removed in the morning. Overnight, the intensive care unit was staffed remotely by Dr. Reed, a teleintensivist-an off-site critical care specialist with real-time access to patient monitors, test results, and audiovisual information from several hospital ICUs. The rural hospital, unable to find a specialist physician to staff the intensive care units, had established the teleintensivist care model the previous year. When Sarah asked Dr. Gray who would be taking his place, he explained that all of the patients were closely watched by a remote physician on a monitor and that nurses-and additional physicians, although they were not directly involved in Mrs. Mason's case-were available in the unit at all times in case a patient's condition became unstable. Sarah asked, "Couldn't we arrange for her to go somewhere where there's a doctor actually on duty in-person at night?" Dr. Gray paused before replying. The nearest hospital was several hours away, arranging a transfer would take several hours and might be dangerous due to the distance and the severity of Mrs. Mason's illness. Commentary The rapid progress of technology in medicine has created new possibilities that might improve the level of care available to patients around the world but also raise serious questions about the consequences of moving away from traditional patientphysician interactions. Telemedicine, an area of particularly rapid growth, involves