Stage I and II Hodgkin's Disease in the Pediatric Population

Abstract

Between January 1, 1970, and December 31, 1990, 42 consecutive pediatric patients were treated at the Medical College of Wisconsin Affiliated Hospitals for early-stage Hodgkin's disease. Thirty patients were clinically staged. Twelve underwent staging laparotomy as a part of staging work-up. Thirty-one patients were treated with radiation therapy (RT) alone. Eleven were treated with combined chemotherapy and RT. For the entire group, overall survival at 5, 10, and 15 years was 98, 98, and 92%, respectively. Disease-free survival was 86, 86, and 79, respectively. There was no significant difference in overall survival or disease-free survival comparing clinically versus pathologically staged patients. There was a trend toward improved disease-free survival favoring pathologically staged patients; however, this difference did not reach statistical significance (p = 0.07). The long-term results of this series fail to show statistically significant superior disease-free or overall survival with surgical staging.

Maladie de hodgkin et cancer colique secondaire: à propos d’un cas

“…Le taux de survie des enfants et adolescents suivis pour une maladie de Hodgkin (MDH) atteint approximativement 90% après 10 ans de traitement [1]. Mais, en dépit des progrès thérapeutiques réalisés ces 30 dernières années, les jeunes patients recevant précocement des traitements plus agressifs demeurent à risque de complications tardives, notamment les cancers secondaires.…”