“… 3 , 4 , 5 This novel staging of cardiac damage has been validated in multiple cohorts for AS, including moderate and severe symptomatic and asymptomatic patients. 3 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 Moreover, this classification has been validated in other valvular heart diseases including mitral regurgitation, 24 , 25 , 26 , 27 , 28 tricuspid regurgitation, 29 , 30 and aortic regurgitation. 31 …”