Standard procedures for the diagnostic pathway of sleep‐related epilepsies and comorbid sleep disorders: A European Academy of Neurology, European Sleep Research Society and International League against Epilepsy‐Europe consensus review

Nobili, Lino; Weerd, Al de; Rubboli, Guido; Beniczky, Sándor; Derry, Christopher P.; Eriksson, Sofia; Halász, Péter; Högl, Birgit; Santamaría, Joan; Khatami, Ramin; Ryvlin, Philippe; Rémi, Jan; Tinuper, Paolo; Bassetti, Claudio; Manni, Raffaele; Koutroumanidis, Michalis; Vignatelli, Luca

doi:10.1111/jsr.13184

Cited by 15 publications

(7 citation statements)

References 173 publications

(254 reference statements)

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“…The major diagnostic sections of sleep disorders classified by the third edition of the International Classification of Sleep Disorders-3 (ICSD-3) are listed as follows: insomnia, sleep-related breathing disorders, central disorders of hypersomnolence, circadian rhythm sleep-wake disorders, parasomnias, sleep-related movement disorders, and other sleep disorders [ 11 ]. The standard procedures of diagnosing sleep disorders in patients with epilepsy have been issued recently by the European Academy of Neurology and the European Sleep Research Society [ 12 ].…”

Section: Sleep Disorders In Patients With Epilepsymentioning

confidence: 99%

The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy

Peng

Ding

Wang

2021

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Background: There is a complex and interactive relationship between sleep and epilepsy. Sleep disorders are common in patients with epilepsy, and methods for managing sleep disorders in patients with epilepsy are limited. Objective: This review is to address the relationships among sleep, sleep disorders, and epilepsy, focusing on the managements for sleep disorders in epilepsy, including some complementary and alternative therapies. Methods: The terms related to “sleep” and “epilepsy” were searched in “Pubmed” and “Cochrane Library”. Results: Sleep stages differently affects both of seizures and interictal epileptiform discharges. Seizures disrupt sleep architectures greatly, especially when arising from sleep in the night. Insomnia and obstructive sleep apnea (OSA) are the most frequent types of comorbid sleep disorders in patients with epilepsy. Pharmacological agents with both anti-convulsant and sedative effects are the priorities for comorbid sleep disorders in epilepsy. Continuous positive airway pressure (CPAP) therapy is the most effective non-pharmacological method to improve OSA and reduce seizures. Complementary and alternative therapies such as Chinese traditional medicine, cognitive behavioral therapy, meditation, yoga, neurofeedback, and acupuncture may have benefits on reducing seizures and improving sleep quality simultaneously by alleviating stress and seizure triggers, however, evidence-based therapies are still in deficiency. Conclusion: Managements for sleep disorders in patients with epilepsy are challenging. Large sample randomized controlled trials are in demand in the future.

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Section: Sleep Disorders In Patients With Epilepsymentioning

confidence: 99%

The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy

Peng

Ding

Wang

2021

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“…Epilepsy and sleep interact in multiple ways ( Malow, 2007 ; Grigg-Damberger and Foldvary-Schaefer, 2021 ; Moore et al, 2021 ). On the one hand, sleep has a modulating effect on epileptic activity; some epilepsy syndromes are characterized by seizures occurring almost exclusively during sleep, or by a major activation of inter-ictal epileptiform discharges during sleep, especially NREM sleep ( Frauscher and Gotman, 2019 ; Nobili et al, 2020 ). This activating effect of NREM sleep on epilepsy is modulated by the depth of sleep: lighter stages of NREM sleep promote seizures, whereas deeper stages associated with high amplitude slow waves are more likely to enhance inter-ictal epileptiform discharges ( Minecan et al, 2002 ; Frauscher et al, 2015 ).…”

Section: Epileptic Seizures and Dreamsmentioning

confidence: 99%

Relationship Between Epilepsy and Dreaming: Current Knowledge, Hypotheses, and Perspectives

et al. 2021

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The interactions between epilepsy and sleep are numerous and the impact of epilepsy on cognition is well documented. Epilepsy is therefore likely to influence dreaming as one sleep-related cognitive activity. The frequency of dream recall is indeed decreased in patients with epilepsy, especially in those with primary generalized seizures. The content of dreams is also disturbed in epilepsy patients, being more negative and with more familiar settings. While several confounding factors (anti-seizure medications, depression and anxiety disorders, cognitive impairment) may partly account for these changes, some observations suggest an effect of seizures themselves on dreams. Indeed, the incorporation of seizure symptoms in dream content has been described, concomitant or not with a focal epileptic discharge during sleep, suggesting that epilepsy might directly or indirectly interfere with dreaming. These observations, together with current knowledge on dream neurophysiology and the links between epilepsy and sleep, suggest that epilepsy may impact not only wake- but also sleep-related cognition.

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“…Both, sleep disorders and epilepsy are common. They may co-occur in the same patient ( Manni and Terzaghi, 2010 , Grigg-Damberger and Foldvary-Schaefer, 2021 , Kataria and Vaughn, 2016 , Malow, 2007 , Nobili et al, 2020 , Unterberger et al, 2015 ) and exert mutual influence on each other. For instance, obstructive sleep apnea (OSA) is common in patients with epilepsy ( Bergmann et al, 2020 , Manni et al, 2003 , Liu and Wang, 2017 ) and may increase the risk of epileptic seizures during sleep, ( Malow et al, 2000 ) although this is controversial ( Vendrame et al, 2014 ).…”

Section: Introductionmentioning

confidence: 99%

The additional diagnostic benefits of performing both video-polysomnography and prolonged video-EEG-monitoring: When and why

Bergmann

Brandauer

Stefani

et al. 2022

Clinical Neurophysiology Practice

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Standard procedures for the diagnostic pathway of sleep‐related epilepsies and comorbid sleep disorders: A European Academy of Neurology, European Sleep Research Society and International League against Epilepsy‐Europe consensus review

Cited by 15 publications

References 173 publications

The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy

The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy

Relationship Between Epilepsy and Dreaming: Current Knowledge, Hypotheses, and Perspectives

The additional diagnostic benefits of performing both video-polysomnography and prolonged video-EEG-monitoring: When and why

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