Standardization of Bee Brood Homogenate Composition

Lazaryan, D. S.; Sotnikova, E. M.; Evtushenko, N. S.

doi:10.1023/b:phac.0000016077.99039.4b

Cited by 8 publications

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“…On the other hand, drone larva homogenate is completely not perceived as a food product, although it has similar chemical composition and physico‐chemical properties to those of royal jelly . In Western Europe, the homogenate is treated as a waste and is not considered to be a potential source of valuable biologically active ingredients.…”

Section: Introductionmentioning

confidence: 99%

“…[6,[11][12][13][14][15][16][17][18] On the other hand, drone larva homogenate is completely not perceived as a food product, although it has similar chemical composition and physico-chemical properties to those of royal jelly. [19,20] In Western Europe, the homogenate is treated as a waste and is not considered to be a potential source of valuable biologically active ingredients. The quantitative analysis showed that the total protein content in the fresh larvae homogenate is 9.4/100 g, the amino acids 7.9/100 g, lipids 4.7/100 g, including fatty acids 4.0/100 g. [6,21,22] The saturated fatty acids (52%, mainly palmitic and stearic acids) predominate in its composition of fatty acids.…”

Section: Introductionmentioning

confidence: 99%

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LC/MS/MS analysis of α‐tocopherol and coenzyme Q₁₀ content in lyophilized royal jelly, beebread and drone homogenate

et al. 2016

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This study shows the results of application liquid chromatography-tandem mass spectrometry (LC/MS/MS) for assay of the content of α-tocopherol and coenzyme Q in bee products of animal origin, i.e. royal jelly, beebread and drone homogenate. The biological matrix was removed using extraction with n-hexane. It was found that drone homogenate is a rich source of coenzyme Q . It contains only 8 ± 1 µg/g of α-tocopherol and 20 ± 2 µg/g of coenzyme Q . The contents of assayed compounds in royal jelly were 16 ± 3 and 8 ± 0.2 µg/g of α-tocopherol and coenzyme Q , respectively. Beebread appeared to be the richest of α-tocopherol. Its level was 80 ± 30 µg/g, while the level of coenzyme Q was only 11.5 ± 0.3 µg/g. Copyright © 2016 John Wiley & Sons, Ltd.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

LC/MS/MS analysis of α‐tocopherol and coenzyme Q₁₀ content in lyophilized royal jelly, beebread and drone homogenate

et al. 2016

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“…As a result, moves were made to standarise this non-traditional product of bee-keeping (Lazaryan et al, 2003;Budnikova, 2011, Krasovskaya, 2011. In spite of the above, the chemical composition of honeybee brood has not received as much attention as that of other bee products.…”

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confidence: 99%

GC-MS investigation of the chemical composition of honeybee drone and queen larvae homogenate

Isidorov

Бакиер

Stocki

2016

Journal of Apicultural Science

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A b s t r a c tHoneybee larva homogenate appears to be underrated and insufficiently explored but this homogenate is an exceptionally valuable honeybee product. Drone larva homogenate is very nutritional due to its high content of proteins, free amino acids, lipids, and carbohydrates. Moreover, the biological characteristics of honeybee larvae indicate the presence of chemical substances that may be pharmacologically active. In spite of the above, the chemical composition of honeybee larva has not gained as much attention as that of other bee products. In this study, the chemical composition of honeybee brood homogenate has been investigated using gas chromatography/mass spectrometry. As a result, it was possible to isolate as many as 115 extractive organic compounds from 6 samples of crude queen and 9 samples of drone homogenate. �he main groups of sub�The main groups of substances extracted from either type of homogenate were composed of free amino acids and carbohydrates. The relative content of amino acids in queen homogenate as well as the share of essential amino acids were found to be higher than in the drone homogenate. Disaccharide trehalose was the dominant sugar in the queen larvae, whilst glucose prevailed in the drone larvae. Comparative chemical analyses of honeybee queen and drone larva homogenates have allowed us to make a preliminary inference about a higher overall value of the former.

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“…Table 1. Physical properties and chemical composition of raw drone brood homogenate in comparison with the apilarnil product [17,[34][35][36][37][38] as well as royal jelly [35,[38][39][40]. Drone brood homogenate is a milky, dense substance with creamy consistency.…”

Section: Functional Components Of Drone Broodmentioning

confidence: 99%

Drone Brood Homogenate as Natural Remedy for Treating Health Care Problem: A Scientific and Practical Approach

Sidor

Dżugan

2020

Molecules

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Drone brood homogenate is a little-known bee product used in folk medicine to treat various health problems. It is a very nutritious milky substance with high content of nutrients: proteins, lipids, fatty acids, carbohydrates, vitamins (A, B, E and D), and minerals. Moreover, when collected on early stage of larvae development, it is, most of all, rich source of sex hormone (testosterone, progesterone and estradiol). Some beekeepers consider drone brood as a waste product, although in some countries they use it to fight Varroa. Meanwhile, in many scientific reports a curative effect of bee drone homogenate in treating urgent global health problems have been confirmed, including ovarian dysfunction in women and male infertility, thyroid and immunity disorders, as well as malnutrition in children. A few dietary supplements based on drone brood are available online. Many patents relating to drone brood-based dietary supplements have been filed in Russia, but their prevalence in EU countries is still limited. Further research is needed to fully recognize the pharmacological activity and increase the use of drone brood.

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Standardization of Bee Brood Homogenate Composition

Cited by 8 publications

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LC/MS/MS analysis of α‐tocopherol and coenzyme Q₁₀ content in lyophilized royal jelly, beebread and drone homogenate

LC/MS/MS analysis of α‐tocopherol and coenzyme Q₁₀ content in lyophilized royal jelly, beebread and drone homogenate

GC-MS investigation of the chemical composition of honeybee drone and queen larvae homogenate

Drone Brood Homogenate as Natural Remedy for Treating Health Care Problem: A Scientific and Practical Approach

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Standardization of Bee Brood Homogenate Composition

Cited by 8 publications

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LC/MS/MS analysis of α‐tocopherol and coenzyme Q10 content in lyophilized royal jelly, beebread and drone homogenate

LC/MS/MS analysis of α‐tocopherol and coenzyme Q10 content in lyophilized royal jelly, beebread and drone homogenate

GC-MS investigation of the chemical composition of honeybee drone and queen larvae homogenate

Drone Brood Homogenate as Natural Remedy for Treating Health Care Problem: A Scientific and Practical Approach

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LC/MS/MS analysis of α‐tocopherol and coenzyme Q₁₀ content in lyophilized royal jelly, beebread and drone homogenate

LC/MS/MS analysis of α‐tocopherol and coenzyme Q₁₀ content in lyophilized royal jelly, beebread and drone homogenate