Statistical Method Selection İn Medical Research

Eroğlu, Özgür

doi:10.26449/sssj.1219

Cited by 5 publications

(3 citation statements)

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“…The odds ratio (OR), 95% confidence interval, the positive and negative predictive values were calculated to determine the risk of predicted events. The differences were considered significant at p<0.05 [1,7].…”

Section: Materials and Methods Of Researchmentioning

confidence: 99%

The impact of obesity on the development of certain cancers in patients with type 2 diabetes

et al. 2021

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The aim of the study was to investigate the effect of obesity on the development of cancer of certain localizations in patients with type 2 diabetes mellitus (T2D) and to explain the association mechanisms of obesity in diabetes and cancer. The study included retrospective analysis of first time diagnosed cancer cases in patients with T2D in 2012-2016 in Ivano-Frankivsk region. Analysis of the data was carried out using Statistica 12.0 (StatSoft Inc., USA) program. The data are presented in the tables as M ± SD (M ± standard deviation). Differences between the studied parameters were determined using the ANOVA- test, taking into account the Bonferroni correction. The relationship between the studied data was evaluated using the criterion of chi-square with Yates correction (χ²). The odds ratio (OR), 95% confidence interval, the positive and negative predictive value were calculated to determine the association between two events. The differences were considered significant at p < 0.05. According to the results, 533 cases of the first time diagnosed cancer were detected in patients with T2D. It was found that obesity is inherent in women with breast, uterine, ovarian and colorectal cancer; for men with prostate cancer and with colorectal cancer. According to the criterion of χ², the effect of obesity on the incidence of breast cancer in women (x2=8.46; p<0.05), and prostate cancer (x2=7.02; p<0.05) and colorectal cancer (x2=7.94; p<0.05) in men was proven. OR revealed an increased risk of breast cancer in women [OR=2.06; 95% CI (1.28-3.29); p<0.05], and prostate cancer [OR=2.94; 95% CI (1.37-6.32); p<0.05] and colorectal cancer [OR=2.87; 95% CI (1.42-5.82); p<0.05] in men associated with obesity. Thus, among patients with T2D, obesity increases the risk of breast cancer in women, prostate cancer and colorectal cancer in men. The mechanisms of association of obesity and cancer in patients with T2D are hyperglycemia, hyperinsulinemia, cytokine imbalance, hyperestrogenism (in estrogen-dependent cancer), and intestinal dysbiosis (in colorectal cancer).

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Section: Materials and Methods Of Researchmentioning

confidence: 99%

The impact of obesity on the development of certain cancers in patients with type 2 diabetes

et al. 2021

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“…Parametric (Student) and nonparametric (Wilcoxon) research methods were used for statistical data processing. Probable changes were considered at p ≤ 0.05 (Eroglu and Yuksel 2019).…”

Section: Methodsmentioning

confidence: 99%

Experimental research of garden spinach extract as a potential anabolic medicinal product

Nykyforuk¹,

Фіра²,

Lykhatskyi³

et al. 2020

PHAR

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Disorders of protein metabolism – one of the pathologies, the treatment of which is an urgent problem of modern medicine and pharmacy. The importance of the problem is stipulated due to the prevalence of diseases that are accompanied by a violation of protein metabolism in the body. Restoration of protein resources during such conditions requires adequate intake of structural components from the outside – proteins, amino acids and other biologically active substances-correctors of protein metabolism. In recent decades, much attention has been paid to the discoveries of anabolic agents of natural origin, especially from plants. We conducted research on the study of the anabolic and antioxidant properties of dry extract of spinach garden leaves on the model of food deprivation in rats. Established, that the dry extract at the dose of 100 mg/kg body weight of animals prevents the development of organic disorders of protein metabolism, oxidative stress, prevents a sharp decrease in body weight and slows down the generalized catabolism caused by starvation in rats. Under the influence of the extract on the model of food deprivation, the diuretic function of the kidneys is preserved at the physiological level.

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“…The difference of probability values was p≥0.95 (P significance level). Differences were considered probable at p˂0.05 [446].…”

Section: Romanian Researchers Have Shown Advantages Of Lutrol F 127 P...mentioning

confidence: 99%

Scientific Foundations in medicine and Pharmacy

Vladlenov¹

2022

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All rights reserved. Printed in the United States of America. No part of this publication may be reproduced, distributed, or transmitted, in any form or by any means, or stored in a data base or retrieval system, without the prior written permission of the publisher. The content and reliability of the articles are the responsibility of the authors. When using and borrowing materials reference to the publication is required. Collection of scientific articles published is the scientific and practical publication, which contains scientific articles of students, graduate students, Candidates and Doctors of Sciences, research workers and practitioners from Europe and Ukraine. The articles contain the study, reflecting the processes and changes in the structure of modern science.

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Statistical Method Selection İn Medical Research

Cited by 5 publications

References 0 publications

The impact of obesity on the development of certain cancers in patients with type 2 diabetes

The impact of obesity on the development of certain cancers in patients with type 2 diabetes

Experimental research of garden spinach extract as a potential anabolic medicinal product

Scientific Foundations in medicine and Pharmacy

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