“…Hoping not to offend the more sophisticated of our readers, we have nevertheless attempted to avoid highly technical terminology in introducing the various topics, so that the review may be of some value to those whose background is primarily in analytical chemistry rather than in mathematical statistics. Of the several review articles which have appeared since the previous article in this series (223), Kaiser's two-part review (278,279) is one of the most relevant to analytical chemistry. He treats the concept of "quantitation" quite broadly, ranging from statistical analysis to information theory.…”